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{
    "metadata": {
        "accession": "A0A8C9NDU9",
        "id": "A0A8C9NDU9_SERCA",
        "source_organism": {
            "taxId": "9135",
            "scientificName": "Serinus canaria",
            "fullName": "Serinus canaria (Island canary)"
        },
        "name": "Histone-lysine N-methyltransferase ASH1L",
        "description": [
            "Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3. Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. The physiological significance of the H3K9me1 activity is unclear"
        ],
        "length": 3036,
        "sequence": "MLCVFSSLRVKDAECPWWKSSAEEHISVNLPSQSAAGKYSVMDPRSSAMLALASDSEGFAGKSPSVANIGTLVGKGEAELEGKKEEEEGKKKSREGSTESSKSEALGDAQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTSIKQPRRAPKGGKMTEEKSEHCPSKQDPPKAYKKAGEVAAVELHVEEGIEVETAPLSKKVSPLHSEMTDYIKSSPPALISSHNSDLKDRTEINGATTVTEKLAQLIATCPPSKSSKTKQKKPGSGNGTTSGLVKDSGKKLPGAISAGGLVNKDLVKKLPGSGLAVGLVNKDSGKKPLGIGSAAILVNKDSGKKPQAISPLIGLVNKDSGKRPPGISTPTGLVHKDSGKKQPVSSSAVGLISKDVGRKLPGISSPAALPTKEPLKKPVGISTPSGLVNKDAGKKLLGINSPTGLLSKDSGRKMPGTGNSTALVNKDSGRKTPGIGSPMGLVSKDPGRKVPGISSPVGLVSKECGKKPAGIGSPAGLATKDSGALKADALVPSSEPFKLPCNSNLSSLESHEPADLLKENTTSKTFEKHIMRQSKESILDKFSIRKEIADVGKEMFSEGMCVPQDAYSSSEKGIYETSKHEKQPPVYCTSPDFRTGGASEVSTAKSPFSAVGEGNLPSPSPTVSVPTLNRSLSTASSQLASNSLHLSSTAELLEGISDPVGKTPFSSDSSLLGLNRTLSHTLSTDFKGAEKDLSDSKASYVETSRTSPPTGKKPILAAETSIHATVTPSVVSFTSLFGSKQFLKIGAIAASEKSCQGAKNLSSTQQSKPLKKRKGRKPRWTKVVSRSACRPPKGLELERSELFKNISYSALSSSNLEQAKFLKNIGSSSFVEHEFVKHQLPKLNEANGQSLALLAETDKQAPKFYSSHKQPSSLCMSDDFLPDIYKPKRGRPKSKEMPELEGPPKRTLKIPASKVFSVQSKEEQEPPILQPEVEIPSLKQSLSGQAFPKKRGRPKRQIRSSIKMKPPILSVAPFVGTENSSKMGPESEQHRPGEFFERKDQLRGPEEVQSPSICSMSDLEVDSDRKVAKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSTVEPNTKGKMQSKLHNTVSTLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKAVLNGLLASSAASLTVLEKSAQQAPGTSLGQVLPHLLPSAATPPEILPSPVCSQSSAVSGGQSPVSSDAGFIEPSSVPYLHLHSRQGSVVQTLAMKKAAKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKKRHSFDHVSLIPAETSTVLSNLKEKHKHKCKRRSHDYLSYDKMKRQKRKRKKKYPQLRGRQDPDFLAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPTFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLAAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHTGHLLLNPTKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMLEHKHRHRHKHREHRSSSEQPQVSMDTIAANSSSRTVLESLKRYRFGKEAVGDRYKHKEKHRCHMACPHLSPSKGLLSRDEQWVRREPSEANSLALGLQTPLQIDCSENSPALSLGGFTPSSEAASSDEHTNLFTSAIGSCRVSNSASTNGRKKLPESPGLFGGQDAALGRALRKEPVPSSLEKALQPLAGTLPSQEKPSQRQSESTNCSPSRKRSTSESTSSPGVAVPARAARLAPAAEDAVDALLQRMAQQQDGPPPLDKGLEGVMGSPPSASPARSHSRDRAPGKQDAPEGASLPGTYSPRHLKRSVVEAMQRQARKMCNYNKILATKKNLDHVNKILKAKKLQRQSRTGNNFVKRRPGRPRKYPMQAVVSVQALQAARMVSQELQDRQQSSSPLHLGPDTITDVIEAVVQSVSLDPEQRKGWKRKRWLPEEQARKRHKSLPEDEQESSKSFSETVAEPPSPHEALGKPPESESPEQPLPPLSQREKKAPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEHGLFPAPIHVGKYLRQKRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPEDDSGKGCVEDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCNPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFDKCRGIIGGKSQRMNGLSSKSNQPVSTHRRPGRSKEKRKSKHKLKKRRGHIPEEPSESVNAPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHVSDSMHSSSLYTRWNGICRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKEICDSIIAYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLATIEKQILTGYYKTVEAFDGDMLKVFRNAEKYYGRKSPTGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVCDKDNGHEKDEDVIRCICGLYKDEGLMIQCEKCMVWQHCDCMGVNSDVEHYLCEQCEPRAVNREVPMIPRPHYAQPGCVYYICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRKFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKRDFSPHYVPDNYKRNGGRSSWKSDRSKPQIKDLNQEEDSLPLMEEVLGAPEQAPGELPSPEEPDKEPVPSESCEAEKKGEENPSDTRPLCSPEERRHLQRERLNQILLNLLEKIPGKNGEASGPGSPAGLGSLG",
        "proteome": "UP000694409",
        "gene": "ASH1L",
        "go_terms": [
            {
                "identifier": "GO:0003677",
                "name": "DNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0042054",
                "name": "histone methyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003682",
                "name": "chromatin binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "3c477914e3aac30db04a16a90a1a630f2cd4a3b0",
        "counters": {
            "domain_architectures": 1172,
            "entries": 44,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 8,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "smart": 6,
                "ssf": 3,
                "cathgene3d": 4,
                "profile": 5,
                "pfam": 5,
                "cdd": 4,
                "panther": 1,
                "prosite": 1,
                "interpro": 15
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1172
        }
    }
}