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{
    "metadata": {
        "accession": "A0A8C5KEG8",
        "id": "A0A8C5KEG8_JACJA",
        "source_organism": {
            "taxId": "51337",
            "scientificName": "Jaculus jaculus",
            "fullName": "Jaculus jaculus (Lesser Egyptian jerboa)"
        },
        "name": "Receptor-interacting serine/threonine-protein kinase 2",
        "description": [
            "Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments"
        ],
        "length": 539,
        "sequence": "TMDGDAICSALPTIPYHKLAELRYLSRGASGTVSAARHADWRIQVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWSLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFQEVTNPLQIMYSVSQGHRPDTNEENLPFDIPHRTLMISLIQSGWAQNPDERPSFLKCLIELEPVLTTFEEITFLEAVIQLKKTKLQSASTDHLYSNKKMDLSLNIPVNNSPQEESCGSSLLHISNNSGTSRSLSAPPDKNFLSGQSPDRSSMKPHHCAVNHSWDTSASASQKATLCDHRTTLCSSAIINPLLAEGNSERMQLGIAQQWIQSKREDIVSQMTEACINQSLDALLSRDLLMKEDYELISTKPTRTSKVRQLLDTSDIHGEEFAKVIVQKLKDNKQMGLQPYPEVLVISRAASSSFLQNKSL",
        "proteome": "UP000694385",
        "gene": "Ripk2",
        "go_terms": [
            {
                "identifier": "GO:0004672",
                "name": "protein kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006468",
                "name": "protein phosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0042981",
                "name": "regulation of apoptotic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004674",
                "name": "protein serine/threonine kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0043065",
                "name": "positive regulation of apoptotic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005737",
                "name": "cytoplasm",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "9a9b4eb4c9be1f207745cfd1abb435ea7ba58c4e",
        "counters": {
            "domain_architectures": 885,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "profile": 2,
                "smart": 1,
                "pfam": 2,
                "cdd": 1,
                "pirsf": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 9
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 885
        }
    }
}