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{
    "metadata": {
        "accession": "A0A8C3ML71",
        "id": "A0A8C3ML71_GEOPR",
        "source_organism": {
            "taxId": "87175",
            "scientificName": "Geospiza parvula",
            "fullName": "Geospiza parvula (Small tree-finch)"
        },
        "name": "Phosphoinositide 3-kinase adapter protein 1",
        "description": [
            "Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL"
        ],
        "length": 781,
        "sequence": "MAAPGAPGEYDVLIVYASDAAEWCQYLQNLFLFTWQVRKHRILSYQLQDHSAISPQELDLFSRSRSIILLLSAELVQSFYIPHIQQSLQEALWPPCKVVKLFCGVTDCDDYLTFFKDWAQWQELTNDDEPDAYLAAVEKAISEDSGCDSVTDTETEDEKNPADSHRLAMSEEHGSSRSTGDCPVVQPSRIQCGVQTTVYIIMKCKLDGGMKTEVEFSPENASSVRVLAEMENEYTISVKAPNLTSGTVTLQIYSGDLMVGQTSVTYHTDMEEISNLLANAANPVQFMCQAFKIVPYSIEALDKLLTESLKKNIPASGLHLFGINQLEEEDMTANQRDEELPTLLHFSARYGLKNLTALLLTCPGALQAYSVANKYGHYPNTIAEKHGFKDLRQFIDEYVETADMLKSHIKEELMQGEEDESVYESMAHLSTDLLMKCSLNPGSDEELYESMAGFVPSAPEDLYVEMLQSKPDTPVAGDEVSITTKDSMLRKFLEGGSMDVPDSEEGGHEQYGEDVYYSVEQDPFPQEMANRPPVPVPRPESSSPQPDNELYISKIFAQKAQRPENLYVPRGRVKKETIVRPVRDLSQSSIYDPFAGMKTPGQRQLITLQEQVKMGILTVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQMEKQKKDKSADLEITVPIRHSHNTLGKPECGIYEYTPRKNLFPPKRELKRGDWKTESTSSTTSSASNRSSTRSILSVSSGMEGDTEDSEVPETARSRSPVLHQVERLPFPERPPRVPPRGASR",
        "proteome": "UP000694382",
        "gene": null,
        "go_terms": [
            {
                "identifier": "GO:0007165",
                "name": "signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "2fee5d8cf198bb0c711d5b6d9ba63ec34e015f88",
        "counters": {
            "domain_architectures": 927,
            "entries": 13,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "profile": 2,
                "pfam": 3,
                "smart": 1,
                "panther": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 927
        }
    }
}