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{
    "metadata": {
        "accession": "A0A8C0P6Y7",
        "id": "A0A8C0P6Y7_CANLF",
        "source_organism": {
            "taxId": "9615",
            "scientificName": "Canis lupus familiaris",
            "fullName": "Canis lupus familiaris (Dog)"
        },
        "name": "AMSH-like protease",
        "description": [
            "Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains"
        ],
        "length": 436,
        "sequence": "MDQPFTVASLRRLAALPDHTDVSLSPEERVRALSKLGANIAITEDIAPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKKDLLKKYNVEYQEYLQSKNKYKAEILKQLEHQSLIEAERKRVARMRQQQLESEQFLFFEDQLKKQELARGQMRSQEGPAPPEQIDGGAVSCFSAQREESLLGAFADLPAPSRAASCAGHSPPVTRALKPAATLSAVQNLVVEGLRRVVLPRDLCHKFLLLAESNTVRGIETCGILCGKLMHNEFTITHVIVPKQSAGPDYCDVENVEELFGVQDQHGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAVVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKDPRLFSVCKHVLIKDIKITMLDLR",
        "proteome": null,
        "gene": "STAMBPL1",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008233",
                "name": "peptidase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008237",
                "name": "metallopeptidase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0061578",
                "name": "K63-linked deubiquitinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0140492",
                "name": "metal-dependent deubiquitinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016579",
                "name": "protein deubiquitination",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0070536",
                "name": "protein K63-linked deubiquitination",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "b0d3c2234d921e15c4ac0f7103e62095a3f2230d",
        "counters": {
            "domain_architectures": 4918,
            "entries": 14,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "pfam": 2,
                "ssf": 2,
                "cdd": 1,
                "smart": 1,
                "profile": 1,
                "panther": 1,
                "interpro": 4
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 4918
        }
    }
}