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{
    "metadata": {
        "accession": "A0A8B7PZL5",
        "id": "A0A8B7PZL5_HIPAR",
        "source_organism": {
            "taxId": "186990",
            "scientificName": "Hipposideros armiger",
            "fullName": "Hipposideros armiger (Great Himalayan leaf-nosed bat)"
        },
        "name": "Serine protease HTRA3",
        "description": [
            "Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization"
        ],
        "length": 496,
        "sequence": "MWPRARPRPLRRRPAPGPSAASVSPPASGRSSALPPAPGPSAMQARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGESLECTRGVCRCRWAHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSTKALSGRQQLKVQLQNGDTYEATIKDIDKKSDIATIKIHPKKKLPALLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINVSALSPAPGPHPDGEVIGINTLKVAAGISFAIPSDRIVRFLTEFQDKHVKDWKKRFIGIRMRTITPSLVEELKASNPDFPEVGSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLTESPLLLEVRRGNDDLLFNIAPEVVL",
        "proteome": "UP000694851",
        "gene": "HTRA3",
        "go_terms": [
            {
                "identifier": "GO:0005576",
                "name": "extracellular region",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004252",
                "name": "serine-type endopeptidase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006508",
                "name": "proteolysis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "7b375b02671c9e36f05a591177bc204239049686",
        "counters": {
            "domain_architectures": 611,
            "entries": 30,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 5,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 3,
                "smart": 3,
                "ssf": 4,
                "pfam": 4,
                "cathgene3d": 4,
                "cdd": 2,
                "panther": 1,
                "prints": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 611
        }
    }
}