General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "A0A8B7B613",
        "id": "A0A8B7B613_ORYAF",
        "source_organism": {
            "taxId": "1230840",
            "scientificName": "Orycteropus afer afer",
            "fullName": "Orycteropus afer afer"
        },
        "name": "Hexokinase-2",
        "description": [
            "Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis"
        ],
        "length": 917,
        "sequence": "MIASHLLAYFFTELNHDQVQKVDQYLYDMRLSDETLQEISKRFRKEMEKGLGATTHPTASVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVRVTDNGLQKVEMENQIYAIPEDLMRGSGTQLFDHIAQCLANFMGQLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGKDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGMLDDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLTTGHFETKDVSDIEGEKDGVRRAHDILVRLGIDPTQEDCVATHRICQIVSTRSASLCAATLAAVLRRIKENKGEDRLRSTIGVDGSVYKKHPHFAKRLHKAVRRLVPNCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLKLSHEQLLEVKRRMKIEMERGLRKETHTSAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYTIPQEIMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCHQNRLDESILLKWTKGFKVSGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDNFRTEFDVAVDDLSLNPGKQRFEKMISGMYLGEIVRNVLIDFTKRGLLFRGRISERLKTKGIFETKFLSQIESDCLALLQVRSILQHLGLESTCDDSIIVKEVCTVVAQRAAQLCGAGMAAVVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKIMHETVKDLAPRCDVSFLESEDGSGKGAALITAVACRIREAGQR",
        "proteome": "UP000694850",
        "gene": "HK2",
        "go_terms": [
            {
                "identifier": "GO:0004396",
                "name": "hexokinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005536",
                "name": "D-glucose binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0001678",
                "name": "intracellular glucose homeostasis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005975",
                "name": "carbohydrate metabolic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006096",
                "name": "glycolytic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "451f24fa92cfee9623e00c10472050175be3e865",
        "counters": {
            "domain_architectures": 4652,
            "entries": 16,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "ssf": 1,
                "pfam": 2,
                "cdd": 2,
                "cathgene3d": 2,
                "panther": 1,
                "prosite": 1,
                "prints": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 4652
        }
    }
}