General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "A0A7N5KSP6",
        "id": "A0A7N5KSP6_AILME",
        "source_organism": {
            "taxId": "9646",
            "scientificName": "Ailuropoda melanoleuca",
            "fullName": "Ailuropoda melanoleuca (Giant panda)"
        },
        "name": "InaD-like protein",
        "description": [
            "Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Promotes clustering of HT2RC at the cell surface",
            "Scaffolding protein that facilitates the localization of proteins to the cell membrane. Required for the correct formation of tight junctions and epithelial apico-basal polarity. Acts (via its L27 domain) as an apical connector and elongation factor for multistranded TJP1/ZO1 condensates that form a tight junction belt, thereby required for the formation of the tight junction-mediated cell barrier. Positively regulates epithelial cell microtubule elongation and cell migration, possibly via facilitating localization of PRKCI/aPKC and PAR3D/PAR3 at the leading edge of migrating cells. Plays a role in the correct reorientation of the microtubule-organizing center during epithelial migration. May regulate the surface expression and/or function of ASIC3 in sensory neurons. May recruit ARHGEF18 to apical cell-cell boundaries"
        ],
        "length": 1794,
        "sequence": "MKILTQSFNRWLRAGKIEYIDIERPSSGGLGFSVVALRSHNLGEVDIFVKEVQPGSIADRDQRLRENDQILAINHTPLDQNISHQQAIALLQQTTGSLCLVVAREPVHTKSRTSASLTDTTLPETVHWGHIEDVELINDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLRTGDHILRIGGTDVQGMTSEQVAQVLRNCGNSVRMLVARDPVGAISVTPPTPAALPVALPAVAHRSPSADSSLFETYDVELIKKDGQSLGIRIVGYVGTPHTGEASGIFVKSIIPGSAAYHNGQIQVNDKIVAVDGVNIQGFANQDVVEVLRNAGQVVHLTLVRRKTSSSASPLEWPSDRGTAVEPSDTPAHYLTGAVETETNLVGGNEETEERMDNLKNDNIQALEKLENAPDSPENELKSRWENLLGPDYEVMVATLDTQIADDAELQKYSKLLPIHTLRLGMEVDSFDGHHYISSVAPGGPVDTLNLLQPEDELLEVNGVQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVDEPRATEAPLPKMEADHSIDVNTEEDDEGELALWSPEVKIVELVKDHKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERGGELLPGDRLVSVNEYCLENSTLAEAVGVLKAVPPGIVRLGICKPLVADDKEEESHYSLHSNNNEDKTELSGTIHDMNSSLILEAPKEFRDEPYYKEELVDEPFLNLGKAFQSQQKEIDNSKEAWEMHEFLTPRLQEMAEEREMLVDEECELYQDPFQSMDSYPSSHLQEAAPVPSVKELHLGSQWLHDSDSPELQEARSMMSVYSQETQQYGYSTGNMMKENFGISSLPSIPSSEGNSQQGRFDDLENLNSLTKSSLDLGMMIPTDVQGPSLLVELPDVAQRREQEDLPLYQLPRTRVVPKASAYTGTLSARYTTDACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHREAVEAIKNAGNPVVFVVQSLSSTPRVIPSVHNKANKIANNQDQNTEEKKEKRQGTAPPPMKLPPPYKAPSDDSDENEEEYAFTNKKIRQRYADLPGELHIIELEKDKNGLGLSLAGNKDRSHMSIFVVGINPEGPAATDGRMRIGDELLEINNQILYGRSHQNASAIIKTAPSKVKLVFIRNEDAVNQMAVAPFPVPSISPSSLEDQSGTEPVSSEEDGSLEVGIKQLPENESSKLEDISQVAGQGMVAGQQKALECPSDDAVSQMKQQKYSTKVCFSSQETPLAPAPLYHSTDADFTSYGGFQAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGIDLRSASHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDRRLIQGDQILSVNGEDMRNASQETVATVLKCAQGLVQLEIGRLRAGSWTSSRKTSQNSQGSQQSTHSSFPPSLAPVITSLQNLVGTKRATDPSPKSSGTDMGPRTVEIIRELSDALGISIAGGKGSPLGDIPIFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNISAIATQLENMSTSYHLGSPTAEHHPEDTETPPPKIITLEKGSEGLGFSIVGGYGSPHGDLPIYVKTIFTKGAAADDGRLKRGDQILAVNGETLEGVTHEQAVAILKHQTGTVTLTVLS",
        "proteome": "UP000008912",
        "gene": "PATJ",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "be040c8b74bcaacda1b8ccde74608eddd9aa2c35",
        "counters": {
            "domain_architectures": 63,
            "entries": 20,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "cdd": 11,
                "ssf": 1,
                "profile": 1,
                "pfam": 1,
                "smart": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 63
        }
    }
}