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{
    "metadata": {
        "accession": "A0A7N4V0D8",
        "id": "A0A7N4V0D8_SARHA",
        "source_organism": {
            "taxId": "9305",
            "scientificName": "Sarcophilus harrisii",
            "fullName": "Sarcophilus harrisii (Tasmanian devil)"
        },
        "name": "JNK pathway associated phosphatase",
        "description": [
            "Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Activates the JNK signaling pathway. Inhibits T-cell receptor signaling and T-cell mediated immune responses, acting, at least in part, by inducing degradation of E3 ubiquitin ligase UBR2. Dephosphorylates and thereby induces 'Lys-48'-linked ubiquitination of UBR2, leading to proteasomal degradation of UBR2. Dephosphorylates and thereby inactivates tyrosine kinase LCK. Inhibits UBR2-mediated 'Lys-63'-linked ubiquitination of LCK. May play a role in B-cell receptor (BCR) signaling and B-cell function"
        ],
        "length": 205,
        "sequence": "MLLAILPGLYIGNFKDARDAEQLSKNKVTHILSIHDSARPMLEGVKYLCIPAADSPSQNLTRHFKESIRFIHECRLRGEGCLVHCLAGVSRSVTLVVAYIMTITDFGWEDALHMVRAGRSCANPNLGFQKQLQEFEKNEVHQFRQWLKDEYGEDPLKDAEEAKNILGNYKEQARAEPPQQNPSGRRWNSFSTLPSLACNNYTTET",
        "proteome": "UP000007648",
        "gene": "DUSP22",
        "go_terms": [
            {
                "identifier": "GO:0006470",
                "name": "protein dephosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016311",
                "name": "dephosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "15742d355813370d995348f784781e84405a14d7",
        "counters": {
            "domain_architectures": 53529,
            "entries": 13,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "smart": 1,
                "profile": 2,
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 1,
                "pfam": 1,
                "panther": 1,
                "prints": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 53529
        }
    }
}