GET /api/protein/UniProt/A0A7N4PI64/?format=api
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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A7N4PI64",
"id": "A0A7N4PI64_SARHA",
"source_organism": {
"taxId": "9305",
"scientificName": "Sarcophilus harrisii",
"fullName": "Sarcophilus harrisii (Tasmanian devil)"
},
"name": "Platelet-activating factor acetylhydrolase IB subunit alpha1",
"description": [
"Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition. Both alpha1/alpha1 homodimer (PAFAH1B3/PAFAH1B3 homodimer) and alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B2 heterodimer) hydrolyze 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA) more efficiently than PAF, but they have little hydrolytic activity towards 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE). Plays an important role during the development of brain"
],
"length": 229,
"sequence": "MSGDHNPASTPAPGQDVQGDGRWMSLHYRFVADSKDKEPEVVFIGDSLVQLLHQCELWRELFSPLHALNFGISGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNYGHTAEQVAAGIEAIVGLVNQRQPQARVVVLALLPRGQHPNPLRDKNRRVNELVRTALAGRPRAHFLDADPGFVHSDGTISHHDMYDYLHLTRLGYTPVCRALHALLLRLLAAGQGPPQLEPGP",
"proteome": "UP000007648",
"gene": "PAFAH1B3",
"go_terms": null,
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "30e8efcaaad38566460605bbc3ff761efe17bab4",
"counters": {
"domain_architectures": 101760,
"entries": 7,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"cdd": 1,
"pfam": 1,
"panther": 1,
"interpro": 2
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 101760
}
}
}