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{
    "metadata": {
        "accession": "A0A7J8EM33",
        "id": "A0A7J8EM33_ROUAE",
        "source_organism": {
            "taxId": "9407",
            "scientificName": "Rousettus aegyptiacus",
            "fullName": "Rousettus aegyptiacus (Egyptian fruit bat)"
        },
        "name": "Toll-like receptor 9",
        "description": [
            "Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production"
        ],
        "length": 1049,
        "sequence": "MVFPMWTLKSPFLILFNMILISKLGARWFPKTLPCDVSVDNSTTQVIVDCTDKHLTEIPRGIPTNATNLTLTINHIPDISPASFRQLDYLVEIDFRCNCVPIRLGPKDNICTRRPQIKPKSFSELTYLKSLYLDGNQLLEIPLGLPSSLQLLSLEANNIFVIMKENLTELGNIEKLYLGQNCYFRNPCNVSFFIEKDAFRQLLNLKLLSLKDNNITAVPTVLPPTLTELYLYNNIIAKIQEDDFNNLTQLQVLDLSGNCPRCYNVPFPCTPCENNSPLQIHENAFDALTELQVLRLHSNSLRHVPQSWFKNVRKLRELDLSQNYLAKEIADAKFLHLLHNLVQLDLSFNYELQVYQAFMNLSNAFSSLKNLKVLRIKGYVFKELNSINLSPLHQLSNLEVLDLGTNFIKIADLSIFKQFKTLKVIDLSLNKISPSGDSSEVGFCSNTRTSVGTHGPQVYEALHYFRYDEYARSCRFKTKETPSSLSFNEECYKYGKTLDLSRNNIFFIKSSDFQHLSFLKCLNLSGNTIGQTLNGSELRPLVELKYLDFSNNRLDLLYSTAFEELRELEVLDISSNSHYFQSEGITHMLNFTKNLRVLRKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWKDGDNRYLQFFKNLINLEELDISENSLSFLPPGVFDGMPPNLKTLFLVKNGLKSFNWGRLQYLKNLETLDLSYNQLKTVPERLSNCSSSLKKLILHNNQIRHLTKYFLQDAFQLRYLDLSSNKIQIIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPHLATDVTCMGPGAHKGQSVVSLDLYTCELDLTNLILFSLSISAALFLMVVMTASHLYFWDVWYSYHFCKAKVKGYKRLVSPESCYDAFIVYDTKDLAVTEWVLDELVAKLEDPTEKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPLKKSKFLQLRKRLCGSSVLEWPKNPQAHPYFWQCLKNALATDNHVTYSRVFKETV",
        "proteome": "UP000593571",
        "gene": "HJG63_019294",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007165",
                "name": "signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "360df05c2932b59a06ebf1b10d8ec211cb213731",
        "counters": {
            "domain_architectures": 21,
            "entries": 23,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "smart": 3,
                "pfam": 5,
                "profile": 2,
                "panther": 1,
                "prints": 1,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 21
        }
    }
}