GET /api/protein/UniProt/A0A6P7IM23/?format=api
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Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "A0A6P7IM23",
"id": "A0A6P7IM23_9TELE",
"source_organism": {
"taxId": "210632",
"scientificName": "Parambassis ranga",
"fullName": "Parambassis ranga (Indian glassy fish)"
},
"name": "Serine/arginine-rich splicing factor 3",
"description": [
"Splicing factor, which binds the consensus motif 5'-C[ACU][AU]C[ACU][AC]C-3' within pre-mRNA and promotes specific exons inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites within exons. Also functions as an adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export"
],
"length": 168,
"sequence": "MGDPAFHRDCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDASDAVRELDGRTMCGCRVRVELSTGEKRSRSRGPPPSWSRRPRDEHRRRSPPVRRRSPKRRSLSRSRSRSLSRDRRRYRSLSRDRNRRRSRSFSRSRSRSRSTERK",
"proteome": "UP000515145",
"gene": "LOC114435687",
"go_terms": [
{
"identifier": "GO:0003676",
"name": "nucleic acid binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003723",
"name": "RNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "0eb7dadcabd2c02a94f505008bf374cf6371f960",
"counters": {
"domain_architectures": 222038,
"entries": 10,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"profile": 1,
"smart": 1,
"pfam": 1,
"panther": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 222038
}
}
}