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{
    "metadata": {
        "accession": "A0A6P6RGN2",
        "id": "A0A6P6RGN2_CARAU",
        "source_organism": {
            "taxId": "7957",
            "scientificName": "Carassius auratus",
            "fullName": "Carassius auratus (Goldfish)"
        },
        "name": "Large proline-rich protein BAG6",
        "description": [
            "Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms a complex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53 transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulates histone 3 'Lys-4' dimethylation (H3K4me2)",
            "Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC)"
        ],
        "length": 1174,
        "sequence": "MEEPGAVEVTVKTLDSQSRTFTVRGEWTVKQFKEHIASAVEIPVDKQRLIYQGKVLQDERTLTDYNVDGKVIHLVERAPPQSSQSGGGGCGVSGSSGTTDGGSTSSQSSTFPGTPHDRNANNYVMLGTFNLPVNIMDQQQIQMSVQQMLAGVGEMGRNVRVSTSTGSSGSVDVDINVEQSVQSEPRMRLQLAESLLRETQTLIHRLEGQSSEPSSQQENPHPQPSSSSFSAEPMDSSPPPASSSSSASQTDGATHSGPNHPSPLELVEVLSEVRRVEERLRPFMERTHSILGAASSADYNNNTQEREEDQHTLNLIGESLHLLGNTLVALSDLRCNLSSQPPRHLHVVRPMSHYTSPVVLQSGPPHIPIPMNLGSTVTMMANSRQTSEGQAQTSQSSNQSEPQGQAPPPPPNGVSQQMGHGQGSPRVIRITHQTMEPVVMMQMNLDGTTAPIHVPGLPPEFMQAIMHQISQQAVAMATAASAGPQGQQQGTAGTGAQSTDSQAPPPPQARVVITRPTLSPRIPQPMSTRGTTINLRAVPPSAGQQTNQGNPMTSSPLTQMVSGLVGQLLMPLHTGAQTSTTSSSHSFSFSTSTATPSSSSISSSIAPPSSANTSGQTSTHTTSTASVGQSHEGGPGDNLAQLLGSLLGGAGGGVSGAPPSITVTVPGVPAFIQGLSEFIQSGQPVFSPPNQQPPPSQATPSAPSGAAHTTAPQPPGGGGETLSPELFTGIVQGVLSTMMGSLGAGQGNTESIAQFIQRLSQTTNLFTPGTGDAVGFFGDLLSLVCQSFSMVDMVLLLHGNPQPLSRIQPQLTAFFVEHYLRGREPTDANIASAAEDLINGLEEYIAESFSTVTVREGVDIIQTNMSFLRQQFTRIATHILRCTDNTFGQRLLYMCTQGLFECLALNLYCLRGEQRALTTVINHRIRRMSAEVNPSLVNWLTSMMSMRLHVILEHNPVTEEQIQHYVINAQSGSSQRTESDAHASQQSDNTSVEMEEGLSPAPATTAEEVMASSGDTADGDEPPGRPSLEETRGAVAMAPVDREESAGEAEPWAATVPPEWVPIIRHDMLTQRKMKAQPPLSDAYLHGMPAKRRKTTQGEGPHLSLAEAVSRAARTSGVHPVTAPDSLQGELEAPELQEAYTQQVKSDIKKRLSDDPDYNHQRFPNTHRAFSEDS",
        "proteome": "UP000515129",
        "gene": "LOC113119568",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "2110177702f8242d030ec9c43977803beb8e0686",
        "counters": {
            "domain_architectures": 1396,
            "entries": 15,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "profile": 1,
                "cdd": 1,
                "smart": 1,
                "pfam": 3,
                "panther": 1,
                "prosite": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1396
        }
    }
}