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{
    "metadata": {
        "accession": "A0A6P6JYS7",
        "id": "A0A6P6JYS7_CARAU",
        "source_organism": {
            "taxId": "7957",
            "scientificName": "Carassius auratus",
            "fullName": "Carassius auratus (Goldfish)"
        },
        "name": "Dedicator of cytokinesis protein 4",
        "description": [
            "Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration",
            "Has a higher guanine nucleotide exchange factor activity compared to other isoforms"
        ],
        "length": 1953,
        "sequence": "MNMWIPTEHEKYGVVLASFRGTVQHGLPLEIGDTVQILEKWEGWYRGFVLKNPNSKGIFPCSYIHLKNAHIKNKGQFEMVVPTEDSVITEMTSTLRDWGAMWKQLFVKNEGDLFHRLWHVMNEILDLRRQVLVGHLTHDRMRDVKQHITARLDWGNEQLGLDLVPRREFSMVDPDEISITELYRLMENRQRKKETPTPVSTHHLFVHLKSLMSSNLGEELEVFFFIYDSRENKPLSERFFVKLNKNGLPKFPEKTERQCTLFVDLGSGDLRKDVYIVVHIIRIGRMGAGEKKNMCNVQYRRPFGCTVFSIADLLTADSKDDLLLKVYACNTESDWSQIHDNIIKKVNSRYNLSGSNTGLAVALQLLHGDIEQLRREYMVLFTRGVSITKKLGFSDVIMPGEMRNDLYITLEKGEFEKGGKSVARNVEVTVYALDADGQILKGFVAVGSGEPGGDEYHTFVLYHNNSPRWAELIKLPIPVDIFRGSHVRFEFRHCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENANLQDCARYLKLPFSKSDLPGNNQTMKGTKESLWITSFLCSTKLTQNGDMLDLLKWRAHPERISDSLSKLKEIDGSEIVKFLQDTLDTLFGILDESSQKYALKVFDCLVHIINLLQDSKFQHFKPVMDTYIESHFAGALSYRDLIKVLKWYVDRIIEADRQEHIQQVLMATEYIFKYIIQSRRLFALATGGQNEEEFRCCMHELFMSIRFFLSQENKGSRPITQTQAVFLQSFPAVYGELLKLFTLREVATFIRETLGSLPTASQADCPLEAVKLHCIAKTVESQLYTNPESRCILLPVVLRLLQAHMQDQRDLVMCANILTCMVSLLKKDDTEPAASEEVDLIVQSILGVLLRTILEIANRPQPAGHTLRPQVQDVTGEFVSCLLALLRHMKDRHYQQLLQSFTSKDELRDFLLHIFTVFRILIRPEMFPKDWTVMRLVTNNIIITTVLYLSDALRKNFLNDKFDYKVWDSYFCLSVIFINQPCLQLETFSASKRKKILEKYGDMRVMMGCEIFSMWQNLGEHKLNFIPAMIGPFLEVTLVPQPDLRNVMIPIFHDMMDWEQRRSGNFKQVEAKLIDKLDSLLSEGKGDETYRELFNSILLKKIERETWRESGISLIATVTRLMERLLDYRDCMKLGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNYTEASYTLLLYDELLEWSERPLREFLSYPMQSEWQRKEYLHLTIIQNFDRGKCWENGIILCRELADQYESYYDYRNLSKMRMMEASFYDKIMDQQRLEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDQTIYQAEAQYLQIYAVTPIPDSQDVLQRDGVPDNIKSFYKVNHIWRFRYDRPFHKGTKDKENEFKSLWVERTTLTLVQSLPGISRWFEVERRELVEVSPLENAIEVIENKNMQLRTLITQCQTRQMQNINPLTMCLNGVIDAAVNGGLARYQEAFFVKDYIMNHPEDGDKIGRLRELMFEQAQILEFGLTVHEKFVPQDMRPLHKKLVDQFHLMKSSLGIQEFPANVRASPIHFTNGSPRAGRNSVPNIMSPEGGARVVSRRSPLSYPAVKRYSSSSLSSQASNEVSNITGQSESSDEVFNMQPSPSTSSLSSNHSASPNVTSSAPSSARGSPQLSDKRKLSRENCLSPRERPCSAIYPNPLDPAQRPVPHPAGDASLPRSNPNISTPDKVVRPAPSSWSLDMPLSDFNGKCPPVPPRPLYSGSPAKTTRSQSPVMTLCSPQKTSVPPFTPSPTECQSTGLVSNSPVLSGSYSSGISSLSRCSVSEASGTENTPADHALPNSASSGSDELIRRENKTPPPYSMHERNNPRRQVPLPPSLSIPPSIDAPPIPPKPHQIRRQDTEPRRPDQFPRPRPIPRKVSQL",
        "proteome": "UP000515129",
        "gene": "LOC113047926",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005085",
                "name": "guanyl-nucleotide exchange factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005096",
                "name": "GTPase activator activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007264",
                "name": "small GTPase-mediated signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "d5114d2f1b7a4b925b48531e78a189b9d1bc3d0d",
        "counters": {
            "domain_architectures": 680,
            "entries": 35,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 5,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 5,
                "ssf": 1,
                "profile": 3,
                "smart": 1,
                "cdd": 3,
                "pfam": 5,
                "panther": 1,
                "interpro": 16
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 680
        }
    }
}