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{
    "metadata": {
        "accession": "A0A6P6I439",
        "id": "A0A6P6I439_PUMCO",
        "source_organism": {
            "taxId": "9696",
            "scientificName": "Puma concolor",
            "fullName": "Puma concolor (Mountain lion)"
        },
        "name": "Sodium/mannose cotransporter SLC5A10",
        "description": [
            "Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2. Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney"
        ],
        "length": 778,
        "sequence": "MTLGGRGLEVGALDNGGFAQRSVVLAAMGPGTSGSGVRTVTAPRSALGSGVSLHAYDIGVLVVYFVFVIGVGIWVSRFGAWRGRQAQVLTSGWSWSWGPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNMRKPGPGKGRGTHQRSHSTTIRSQATWLLLALGWIFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQIALGWNLYLSTVMLLVVTAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLGFQEVGWYPGLEQRYRQAIPNATVPNTTCHLPRSDAFHMLRDPVNGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKNLSHAKGGSVLGGYLKILPMFFIVMPGMISRALYPDEVGCVDPDVCQSICGARVGCSNIAYPKLVVALMPVGLRGLMIAVILAALMSSLTSIFNSSSTLFAIDVWQRFRKKATEQELMVVGRLFVVFLVVISILWIPIIQSSNSGQLFDYIQSVTSYLAPPITALFLLAIFCKRVTEPGAFWGLMFGLAVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFALLLCGLTAIVIVTVSLCTTPIPEEKLARLTWWTRSHPHSELEKEAPEGTPGTSEMPSGACPPGGGETENSSQDQDQHRGKPYCLSGDLTMATCLLEQISPQHPAYSLMVPFDLRRQCQSDICITISLIFISSLDCKLPHRITVKYRDHCASLCVQALLFQFTLHTIARRVFVKCESRVACPCKILYRASQPSRRPYKNC",
        "proteome": "UP000515131",
        "gene": "SLC5A9",
        "go_terms": [
            {
                "identifier": "GO:0022857",
                "name": "transmembrane transporter activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0055085",
                "name": "transmembrane transport",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "2b2a6841043927bd4b57fafc3151ff36fdcbb775",
        "counters": {
            "domain_architectures": 98886,
            "entries": 9,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "cathgene3d": 1,
                "panther": 1,
                "pfam": 1,
                "ncbifam": 1,
                "prosite": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 98886
        }
    }
}