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{
"metadata": {
"accession": "A0A6P5IVF0",
"id": "A0A6P5IVF0_PHACI",
"source_organism": {
"taxId": "38626",
"scientificName": "Phascolarctos cinereus",
"fullName": "Phascolarctos cinereus (Koala)"
},
"name": "Voltage-dependent L-type calcium channel subunit beta-2",
"description": [
"Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C"
],
"length": 614,
"sequence": "MLVELLVISVLHVAMLKTPKGKNVSWGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLEAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYMEAYWKATHPPSSNPPNPLLSRTLATASLPISSTSASNSQGSQDQRNDYSAPTRSASQAEEEPCLEPVRKSQHRSSSSAQHHNHRGGLGRGLSRQETFDSETQDSRDSAYVEPKEDYSHEHGDHCVPHRDHNHRDEMHGNSDHRHRDSRHRSREADREQDHNEYHKQRSRHKSKDRYCDKDGEVISRKRNEAGEWNRDIYIRQ",
"proteome": "UP000515140",
"gene": "CACNB2",
"go_terms": [
{
"identifier": "GO:0005515",
"name": "protein binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0005245",
"name": "voltage-gated calcium channel activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0070588",
"name": "calcium ion transmembrane transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005891",
"name": "voltage-gated calcium channel complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "2dd7649e7ff0f048a9f2a359d76bba6b148689dd",
"counters": {
"domain_architectures": 9016,
"entries": 21,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 2,
"cathgene3d": 2,
"ssf": 2,
"cdd": 1,
"profile": 1,
"smart": 2,
"panther": 1,
"prints": 2,
"interpro": 8
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 9016
}
}
}