General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "A0A6P5IM60",
        "id": "A0A6P5IM60_PHACI",
        "source_organism": {
            "taxId": "38626",
            "scientificName": "Phascolarctos cinereus",
            "fullName": "Phascolarctos cinereus (Koala)"
        },
        "name": "Tubulin polyglutamylase TTLL11",
        "description": [
            "Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction. Preferentially modifies the alpha-tubulin tail over a beta-tail. Required for CCSAP localization to both spindle and cilia microtubules. Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions"
        ],
        "length": 726,
        "sequence": "MQRACGDGPAELPALEDPGAEGEPDPKAKQNEQRPEPKPDTEPEPELDTKLEPDADPAPDPEPAPAPEPEPERPAEAELQTRVPSSAPLTVQNPAEQGDVSLQERRPRPVARIRTKTKGKKAAGVRVPDESRGRRPLTVTVDSSKARTSLEALKISLRQLKWREFPFGRRLPCDIYWHGVSFHDSDILSGQVNKFPGMTEMVRKITLSRAVRIMQDLFPEEYNFYPRSWILPDEFQLFVAQVRMVKDGDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRMAGNLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLEPLEIYIAKDGLSRFCTEPYQEPNFGNLHHVFMHLTNYSLNIHSGNFIHSDNANTGSKRTFSSILCRLSSKGVDIKKIWSDIISLVIKTVIALTPELKVFYQSDIPAGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEQELSPGVFENVPSLVDEEVKVAVIRDTLRLIDPLKNKKKENRSEQCNKISGMREESREGTDEPQPEDIFDAEAYMNNEASLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTTRLGPTGFRTFIRNCKLSSSTFSMASVDILYIDITRRWNSMGLEQKESGMCLQAFVEAFFFLAQRRFKHSSLQEQVASLVDLCEYHLTLLDEKRLLCSKGTSSGRPPNSSSSQERLPLTQPPNGSFLPRNNTANKFAHYRHPQS",
        "proteome": "UP000515140",
        "gene": "TTLL11",
        "go_terms": [
            {
                "identifier": "GO:0036211",
                "name": "protein modification process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "14078f108af716932125402dd78ea3e32dec3688",
        "counters": {
            "domain_architectures": 1098,
            "entries": 8,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "ssf": 1,
                "cathgene3d": 1,
                "pfam": 2,
                "panther": 1,
                "interpro": 2
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1098
        }
    }
}