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{
    "metadata": {
        "accession": "A0A6P3ISA9",
        "id": "A0A6P3ISA9_BISBB",
        "source_organism": {
            "taxId": "43346",
            "scientificName": "Bison bison bison",
            "fullName": "Bison bison bison (North American plains bison)"
        },
        "name": "Caspase recruitment domain-containing protein 14",
        "description": [
            "Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis"
        ],
        "length": 1002,
        "sequence": "MAELCRTDSSLTSLDEEVLWEMMEDHRCRIVRSIFPSRLTPYLRQAKVLDQLDEEEVLHSPRFNNTAMRVGYLLDLLKTRGKNGAIAFLESLKFHNPDVYTLVTGLQPSVDFTNFSGLMETSKLTECLAGAIGSLQEELSQEKGQKEALLRQCQQLQERLDQAEARAEGLRQLEADHSRMKREVSAHFHEVLKLKDEMLSLSLHYSNALQEKELATTRCRSLQEELYLMKQELQREKMSSSCEREFRERSLKMASDLEPGDEELSRLKEENERLRSLTFSLVEKDILEQNLDEALESRQELVDRIHSLRERAVAAERQRKQYWEEKEQTLLQFQKTKVDCEIYKEKMNALQSQVVELQKERDQAYSARDGAQMEISQNLTEKDALRRKVFELMDQVCELRQQVQRLRVQADSSPGVSAQEVGAREPCPKGKQRLVRMFALCPRDDSNGSSSESQLWSDLSATSSRELVDSFRSSSPAPPSQQSLCKRATEDFWEDPCSSSGCPEILEVDQGGSLVAKKSNADLDFEIVDRADLPESENSLQPSSGDLYLSASCFPVRRRPARKILSQVTVLAFQGDALLEQISVIGGNLTGIFIHRVTLGSAADEMALRSGTQIVMVDYEATEPSSKAVLEGMTLERAVGLLQRVNGFCCLSVKVNMEGYKKLVQDLEAKVATSGDSFYIRVNLALEGRAEGELQVRCNDILHVTDTLFQGSSCWHAHRVGPYSTKGTKHGTIPNYTRAQQLLIALLQDMAHQSTVTRKQSSGGAQKLVRIVSMDRTKASPLWSSFEGSQSDPSRVEGEVDPSTVCFWTESCFTLVPYTLVHPHRPSRPRPVLFVPRVVGKILIEKLCLFQGFKKCPAEYLSQEEYDTSSQRGDIIQEREASGGLYCVTRRAVESLMGKNTHALLDIQLDSVCVLHRMEIFPIIIHVSINEKVAKKFKKALQRLGTTEDQLLEAARQEEAELDKVPCLYSSLAPESWSDLDALLGCVRLAITDEQRKVVWTE",
        "proteome": "UP000515208",
        "gene": "CARD14",
        "go_terms": [
            {
                "identifier": "GO:0042981",
                "name": "regulation of apoptotic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "eede5dad5920dee99d1cbc6b0c16446cf5c706e9",
        "counters": {
            "domain_architectures": 8648,
            "entries": 19,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 3,
                "cathgene3d": 4,
                "ssf": 3,
                "pfam": 1,
                "cdd": 1,
                "panther": 1,
                "interpro": 6
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 8648
        }
    }
}