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{
    "metadata": {
        "accession": "A0A6J3E8F7",
        "id": "A0A6J3E8F7_AYTFU",
        "source_organism": {
            "taxId": "219594",
            "scientificName": "Aythya fuligula",
            "fullName": "Aythya fuligula (Tufted duck)"
        },
        "name": "Ran-binding protein 3",
        "description": [
            "Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export"
        ],
        "length": 518,
        "sequence": "MADLANEEKPAIAPPVFVFQKDKAQKRSADGSSPEDGDESDREDGNYCPPVKRERTSSLTQFPPSQSVTKNNVFMPSSFCEPSTGNSDSEQEEKSSGFRLKPPILIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKAFSQMVLSSGTNGVNIPPDSAATSESLSNATLKSSDSEDKAGECQKKESNNTSDDDSCEKAELNAQQAFVFGQNLRDRVKLGDESDETADVQNAGLPTSDTPSATNYFLQYISSSIENSTNSADASSNKFVFGQNMSERVLSPPKSNEGSTESNKENAATESGSESSSQEATPEKANNISESLAESAAAYTKATARKCLLAKVEVITGEEAESNVLQIQCKLFVFDKNSQSWVERGRGLLRLNDMASADDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEVKNVAPEPEVTQSNEEDSDDDVLAPSGSVGSGPNDEGDGQNVGST",
        "proteome": "UP000504639",
        "gene": "RANBP3",
        "go_terms": [
            {
                "identifier": "GO:0046907",
                "name": "intracellular transport",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "4b4402e44ce7d470ca74eb6ce94573d79fb78383",
        "counters": {
            "domain_architectures": 12060,
            "entries": 10,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "smart": 1,
                "ssf": 1,
                "profile": 1,
                "pfam": 1,
                "cdd": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 12060
        }
    }
}