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{
    "metadata": {
        "accession": "A0A6J2V3F0",
        "id": "A0A6J2V3F0_CHACN",
        "source_organism": {
            "taxId": "29144",
            "scientificName": "Chanos chanos",
            "fullName": "Chanos chanos (Milkfish)"
        },
        "name": "Cadherin-23",
        "description": [
            "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing"
        ],
        "length": 3366,
        "sequence": "MLWHVGSGRMILAKLLLSSFLLHSFSEAFNQPPRFQNYFFQSYLLIYENTPVGASVAQLQAVDPDEEPLIFGVVGEEATRYFAVQENTGMVWLRQPLDRETKSEMQVEFTVSDSQGVVKDTVNIQIGDVNDNAPTFHSQPYTVHIPENTPVGTSVFMVNATDPDQGTGGSVLFSFQPPSRFFSIDGARGTVTVIRPLDYETTSAYQLTVNATDQDKRRPLSSLANLAITITDVQDMDPIFTNLPYSTNIEENSPPGYEVRKITAIDQDQGRPRGIGYTIVSGNTNSMFALDYISGSLTVNGQLDRENPLYSAGFTLTVKGTELNDDRTPSSATVMTTFTILIIDKNDNAPKFNATEYRVRITELAQVGFALPLFIQVEDKDEGVNSIFQVVLTGNNSEHFTISPTSVQGRADIRMRVAVPLDYENIRSYSFSLYANESLSEHVGFARVFIELINENDNRPVFSQTLYNISLPESTTPGTSLVRIQATDNDIGTFGVVRYFFSEEPDQFSLDEETGLVTLRDRLDYELMRRFTLTVLARDGGGEETTGRLRVNVLDVNDNAPVFQKEAYMGSLRENEQAPQQVARVRATDEDSPPNNILTYSIIYASQFRNYFRITMVEGYAVITVDRPLDYELVPGGMIYLTFMARDGGNPPLNSTVPITVELLDENDNPPEFSQSSYIIKIPENIVAGATVLFVNATDLDASREFGQASLIYSLQGSTQFRLNTRSGEITTTALLDREVKSEYILIVRAVDGGVGPLQKTGIATVNITILDINDNAPVWQDEPYRANVVEMSPIDTDVISVLAVDRDNGVNGTVVYSISPQNPFYTINSNTGKIRTSGAVLDRESRDPRATQLMRTIIVSATDLGTPPLQSSVSTTVFVNLLDLNDNDPAFLNLPFVAEVPEGLPIGSSVYRVQVSDPDEDENGMVTMALQMGMPRLDFRLNTSTGVLVSTATLDREQIALYFLRIIAYDAGQYPRTSTSTLTITILDVNDETPTFFPHVYNVSLEENVPRNHVVSRLNCSDNDAGLNAELSYFITGGNQDGKFSVGFRNGVVRTVVGLDRETQASYTLIIEAIDNGPAGGRKTGTATIYVEVLDVNDNRPIFLQNSYETSILETVPRGTSILQVQATDADQGENGRVLYRILSGNSGRRFSIDQLTGLLTRGERALDRETSSSHVLEVEAYNSDQGSMRSSVRVIVYVEDANDEFPVFTQQQYNRLGLRETAGIGTSVIVVRATDPDTGDGGAVAYALVSGSDRKFEVDVSTGLVTTVDYLDYETKTSYLMNVSATDQSPPFHRGFCTVYVTLLNELDEAVAFFSSGYEASIRENIATGTEVVQVQAQSADNLNQLTYRFDPDTSPAALALFKIDSVTGRITVTGLVDRERGDSYTLTVVADDGGPKRDSTVKVSITILDENDNSPEFDITSDLSVSIPEDTPIGQRVAVVLGRDKDAGNNGLVNFTLVAGNMQDVFEIRTVNHTYGEIYVNAALDREAVDRYLLRVRAMDNGSPPRYTDRSLTINILDVNDNTPVVQSPRGYNVSVSENVGGGTSVLRVVATDRDIGPNAMLSYYITAGNQDLTFRMDRITGEMVTRPSPPDRERQQEYQLTVTVEDDGTPPRSTSTTVWVRIVDENDNAPEFPEEEYVTVLSEGPETVGATIATVTAIDPDEGLNGTLRYSIAQGNLGQTFRIYSNTGMIVVVKELDYEISNGHYTLVVTATDQCPIPALRLTSSTTVLINVIDVNDVTPTFPKAFEGPFEVTEGQPGPRVLTLRATDQDSGLNGKVEYSITAGDLKSEFVVSPVEGELRVRRDVELDRETTAYYNITVTARDLGTPPLSSTVVVGVVVLDINDNDPVLLNLPYNTSVSEAAAIHTSVARIQATDSDSGRNALLTYNITGGNMDGAFYINDTTGVVLVNRPLDRERVSEYKLTITVKDNPENPRIARRDSDSLVITVLDENDNKPIFTQTSYRAEISENSPPGTSVLVLNGPVLAVDKDLGQNAVVRYRLLGSRVDLFTVDALTGVVSVRRGAVLDREAFSEPRVELFLVGEDIGGLNSSVPLSITILDQNDNPPVFNPPSFTVHLPENSPTGVVVTQLSATDADSGSNGWLLYRLEGGAQDRFVVDSLSGAVLVGNATLDREERPSYRLVVVATDRGTPPLSGTATLSVVLDDVNDSRPRFLEPVQTINVNESTPPGVVVATLTAEDPDLRPRLEYYIISVEAKDDGNNPVDGLQESFGIDFHTGAVFVRNPLNRELVATFEIIVSVHDNASDVIHQSVSVPNAKLTVNVLDVNDNAPRFRPFGVANFSEKILEGAQPGTTLLSVSAVDPDKGPNGQVIYQLLHLPRGDYVRLEDPSTGKIVANRTVDFEQVQWLNFTVRAQDHGSPPRFAELPVYLRIVDVNDNNPIFTQPSYQKPVFEDIALGTIIVRVSATDADSGLFSVIEYSLVDGEGKFGITPSTGDIYILSPLDRETKDHYTLTAIARDNPGGSPNNRRENSVQVLITVLDVNDFRPRFSERVFSTSVFENEPSGTSVITLTATDLDEGENALLTYSLQGPGADAFSLDADTGLVRSVRLLQSFERFNLTIVATDHGRPPLWGTASLHITVIDVNDNRPVFVRPANGTIMHILEEQPPGLVVYEVFATDEDEGVNGEVRYGFLQTGAGNRDWENFHIDPLTGVITTAVKLDREKQALHSLIVVAYDLGQPVPYETTQPLQVALSDIDDNEPVFLKPPRGSLPYQSLSVPEHSAPGTVVGNVTGAVDADEGSNAVVYYFIAGGDTEGNFGLSTAGVLRVRKDLDREEIPIYSIIIKASSNRNWSLPRSQKSNRAWALDPSHDPTLQEVRIYLEDINDQPPRFTKLEYTAGVAADAKVGSDLIRVQAIDNDIGNNSLVLYHILSIRYIKLQSNDSEDIGNVFIIGETDGIIRTFDLFTAYDPGYFVVEVLARDLAGHSDVAMVGIYILRDDQRVKIVINEIPERVRLFQEEFVNLLSNITGAIVNTDDVQFHVDKKGRVNFAQTDVLIHVVNKQTNRILDVERVIQMIDENKEQLRNLFRNYNILDVQPAVSGRAPDDLTTLQMAIIILAVLLFLAAMLFIFMNWYYRTVHKRKLKAIVAGSTGNQGLMDILDMPNTNKYSFEGANPVWLDPFCRNLELAAQAEHEDDLPENLSDITDLWNSPARTHGTFGREPQASKPEDDRYLRAAIQEYDNIAKLGQIMREGPIKGSLLKVVLDDYLRLKKLFAARLVTKSTSHGDQSSVTELIQSDFDDDDDDRVGVTRGTLRFKHKLPVELRGPDGVHVVHGSTGTLLTSDLNSLPEDDQRALARSLEALHADGGIYAERNARTESAKSTPLHRNKGSDTLSESPLEITEL",
        "proteome": "UP000504632",
        "gene": "cdh23",
        "go_terms": [
            {
                "identifier": "GO:0005509",
                "name": "calcium ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0007156",
                "name": "homophilic cell-cell adhesion",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0007155",
                "name": "cell adhesion",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005886",
                "name": "plasma membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "3fbf2dc65d708052aa81e48e0b359fadef122630",
        "counters": {
            "domain_architectures": 620,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "cdd": 1,
                "profile": 1,
                "smart": 1,
                "panther": 1,
                "prosite": 1,
                "prints": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 620
        }
    }
}