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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A6J2MDC7",
"id": "A0A6J2MDC7_9CHIR",
"source_organism": {
"taxId": "89673",
"scientificName": "Phyllostomus discolor",
"fullName": "Phyllostomus discolor (pale spear-nosed bat)"
},
"name": "Muellerian-inhibiting factor",
"description": [
"Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression"
],
"length": 600,
"sequence": "MSWEMIGAVFQHKHPGPAHISRVAQPFTIPRMWAAPLSRLVLLLWGTLLRAGTPREEALPGESPAGTRGLIFNQDWDWPAPLVWPPSSQQDSLCLVTLGGSGNGSSASLRVVGALRGYEQAFLEALHQAHWGPRDLATFGVCTPSHEHTALTPLQSLQAWLGEPHGQQLVVLHLEEVTWEPTPSLRFQEPPPGESPPELALLVLYPGPGPEVTVTGAGLLGTQSLCLSRDTSYLALAVDHPAGAWQGRGLVLTLQHRGNGTSLSTAQLQLLLFGTDPRCFTRMTPALLLLPRSGRTPMPAQGRQDTVPFPSPSPTLEFKEPQPSADPFLETLTRLVRALRGPPARASLRSLALDPAALVGFPQSLVNLSDPVALERLLDGEEPLLLLSPASATAGDPMSPQGPVSSPWAADLAHRVASELQAAAAELRGLPGLPPAAPPLLARLLELCPGDPGDSGGPGGPLRALLLLKALQGLRTEWRGREWSGPARAQRSAGARAADGACALRELSVDLRAERSVLIPETYQANNCQGSCGWPQSDRNPHYGNHVVLLLKMQARGATLARPPCCVPTAYAGKLLITLSEERISAHHVPNMVATECGCR",
"proteome": "UP000504628",
"gene": "AMH",
"go_terms": [
{
"identifier": "GO:0008083",
"name": "growth factor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008406",
"name": "gonad development",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "22f13bac5db31f04633d2f53e0b703352eccbff6",
"counters": {
"domain_architectures": 859,
"entries": 15,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"profile": 1,
"cathgene3d": 1,
"ssf": 1,
"pfam": 2,
"smart": 1,
"cdd": 1,
"pirsf": 1,
"panther": 1,
"prosite": 1,
"interpro": 5
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 859
}
}
}