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{
    "metadata": {
        "accession": "A0A6J2LLB5",
        "id": "A0A6J2LLB5_9CHIR",
        "source_organism": {
            "taxId": "89673",
            "scientificName": "Phyllostomus discolor",
            "fullName": "Phyllostomus discolor (pale spear-nosed bat)"
        },
        "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial",
        "description": [
            "Mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism"
        ],
        "length": 325,
        "sequence": "MATARGPLRQRLVGLASVRAVSTSSLSTFPKQVKIVEVGPRDGLQNEKNIVPTAVKIRMIDMLSEAGLPVIEATSFVSPKWVPQMADHTEVLKGIQKFPGINYPVLTPNFKGYQAAVAAGAKEVSVFGAASELFTRKNINCSIDESFQQFGQVLQAARAASIPVRGYVSCVLGCPYEGKISPAKVAEVSKKMYAMGCYEISLGDTIGVGTPGLMKEMLSAVMHEVPVSALAVHCHDTYGQALANTLMALQMGVSIVDSSVAGLGGCPYAQGASGNLATEDLVYMLAGLGIHTGVNLQKLLEAGTFICQALNRKTGSKVAQATCKL",
        "proteome": "UP000504628",
        "gene": "HMGCL",
        "go_terms": [
            {
                "identifier": "GO:0003824",
                "name": "catalytic activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016833",
                "name": "oxo-acid-lyase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004419",
                "name": "hydroxymethylglutaryl-CoA lyase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "f61fb8529fe655c17382dbb668bec796bf330a5e",
        "counters": {
            "domain_architectures": 29611,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "profile": 1,
                "cdd": 1,
                "panther": 1,
                "ncbifam": 1,
                "prosite": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 29611
        }
    }
}