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{
    "metadata": {
        "accession": "A0A6J2HQP7",
        "id": "A0A6J2HQP7_9PASS",
        "source_organism": {
            "taxId": "649802",
            "scientificName": "Pipra filicauda",
            "fullName": "Pipra filicauda (Wire-tailed manakin)"
        },
        "name": "Inositol polyphosphate 5-phosphatase OCRL",
        "description": [
            "Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2. Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate. Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes. Involved in primary cilia assembly. Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling"
        ],
        "length": 926,
        "sequence": "MEARAAGRGLLVSTGSGGAGRAGGAGRGAEVSLAAAQSVAGAEVRAGRREPCVLGLARRGGRYGIVIHSQEKENSDPDYIPINSRFKCVQEAEETLLIDIAANSCKVRIQGDETPERLFEIPDEERCLGFLSEVQSIQEAHLKASPEPKDGAIWHQVEKSLPGLLQASPPGALGFEDDFSTLSLEEKRNMQNHQAGSRREPPPPPVPQNRQFPREREGTSRDQPKVTNTMRKMFLPSTQSGQREGLIKHVLAKREKAYINWHNFRFFVGTWNVNGQSPDSFLEPWLVCDTEPPDFYCVGFQELDLSTEAFFYFDSTKEQEWLAAVERALHPQAKYKKVQMVRLVGMMLLVFAKKDHLSNIREIVTESVGTGVMGKMGNKGGVAVRFVFHNTTFCVVNSHLAAHVEDFERRNQDYKDICARMSFETPDDSLPQLNIMKHDVVIWLGDLNYRLCLLDASEVKSLISKNELQKLLTYDQLNIQRTQKKAFADFMEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGGNINQLRYCSHMDLKTSDHKPVSALFRIGVKIVDEQKYRKLFEDIVRIMDRMENDFLPSLELSRREFEFENVKFRQLQKQKFKITNNGQVTCHFSFIPKLNDSHYCKPWLRAEPCEGYLEPDESTDISLDVYVSKDSVTLLNSGEDKIEDILVLHLDRGKDYFLTISGTYLPSCFGTSLEALCRMKRPIREVPVTKLIDLGEDSFLEKEKSVLQMGSLDSEEAGEVPLQVPKEIWLLVDHLFKHACHQEDLFQTPGMQGELEQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDWSHSSRLCRQVILQLPSCHRNVFRYLMSFLRELLRYSEDNNVSVAMIAALFSSLLLRPPPNLMAKQTQQDRQRAINFLYSFLLAGDEE",
        "proteome": "UP000504627",
        "gene": "OCRL",
        "go_terms": [
            {
                "identifier": "GO:0016791",
                "name": "phosphatase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0046856",
                "name": "phosphatidylinositol dephosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0052745",
                "name": "inositol phosphate phosphatase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007165",
                "name": "signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "507a5ff369407f0e4d9e0356b927a1e7b5ab1d68",
        "counters": {
            "domain_architectures": 1154,
            "entries": 26,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 4,
                "pfam": 4,
                "ssf": 2,
                "smart": 2,
                "cdd": 2,
                "profile": 1,
                "panther": 1,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1154
        }
    }
}