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{
    "metadata": {
        "accession": "A0A6J1Z660",
        "id": "A0A6J1Z660_ACIJB",
        "source_organism": {
            "taxId": "32536",
            "scientificName": "Acinonyx jubatus",
            "fullName": "Acinonyx jubatus (Cheetah)"
        },
        "name": "E3 ubiquitin-protein ligase SHPRH",
        "description": [
            "E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'"
        ],
        "length": 1685,
        "sequence": "MSSRRKRAPPVRVDEAKQQQLRWNMDEDRRNEPLILTDEEHPCSGSDFSSAHCIILGDSLQEEVAHRDKKRCLEAVSIAKSVDKEETGGILSPLSVKLNIVISPYHFDNSWRAFLGELTLQLLPEQSLTEDFSERSFTLMSSESSGQFLIYVNSESEDAEKQEKGLNEPVSICDKGIRVESSFSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEGGLAKLDFLSDANSRMKKFNQLMKRVMEKLYNFIIPDVLEEDEEDSESEPEGQDIDELYQFVKQTHQQETQSIHVDVQHPALIPVLRPYQREAVNWMLQQEHFRSAPASENTLHFLWREIVTSEGLKLYYNPYTGCIIRDYPNSGPQLLGGILADEMGLGKTVEVLALILTHTRQDIKQDALTLPEGKVVNYFIPSHQSGGKVKNTETPNTEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDTYDKTKKQAIGSPRKIQKESRKSGNKDTDSEYLPSNTSDDDDDPYYYYYKPRKNRSKFKKKPVLSTKKGKCQPNINLSSQDHCPATSDSGITDVTTSKSTCIFEIKEERGAKDQAESLNPTDGDVPQSNIGSPCNSSDYRFECICGELDQVDRKPRVQCLKCHLWQHAKCVNYEEKNLKIKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCRKNPQLLYSFIAKILWRSAKKDVIDQIQIPPQTEEVHWLHFSPVERHFYHRQHEVCCQDAVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYAVAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLVAKHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQAVQPVQQTVRELQRKIYSNSPWWLNVIHRAIEFSIDEELVQRVRNEITSHYKQQTGKLSMSEKFHDCRGLQFLLTTQMEELNKFQKLVREAVKNLEGPPSRNVIESATICHLRPTRLPLNCCVFCKADELFTEYESKLFSHTVKGQTAIFEEMIEDEEGLVDDRIPTTSRGLWAVSETERSMKALLSFAKSHRFDVEFIDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAIDELAMATERLRVRHPREPKPNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGINPEPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKASQEEDIPVKGSHSTKVEAVVRTLMRIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKHDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAEKSHTNSSVKHPEASVLTLADLADLFTKETEELE",
        "proteome": "UP001652583",
        "gene": "SHPRH",
        "go_terms": [
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003677",
                "name": "DNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006334",
                "name": "nucleosome assembly",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0000786",
                "name": "nucleosome",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0030527",
                "name": "structural constituent of chromatin",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "41db74f835b6a390dfada439655350f9aaac539d",
        "counters": {
            "domain_architectures": 674,
            "entries": 51,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 9,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 4,
                "cathgene3d": 4,
                "smart": 5,
                "pfam": 6,
                "profile": 3,
                "cdd": 5,
                "panther": 1,
                "prints": 1,
                "prosite": 2,
                "interpro": 20
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 674
        }
    }
}