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{
"metadata": {
"accession": "A0A6J1U090",
"id": "A0A6J1U090_9SAUR",
"source_organism": {
"taxId": "8663",
"scientificName": "Notechis scutatus",
"fullName": "Notechis scutatus (mainland tiger snake)"
},
"name": "Solute carrier family 15 member 2",
"description": [
"Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1. In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate. Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs. Transports the dipeptide-like aminopeptidase inhibitor bestatin. Also able to transport carnosine. Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs). Mediates transport of bacterial peptidoglycans across the plasma membrane or, in macrophages, the phagosome membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand"
],
"length": 726,
"sequence": "MDLSEKGDPKKASFLSVSAGSVSPKSVSPPEKISPGICGTHYPLSIAFIVVNEFCERFSYYGMKAVLSLYFLYFLHWDETTSTSVYHAFSSLCYFSPVIGAFIADSWLGKYKTIIYLSIVYIIGHVIKSVGAITSVGNHITHVILSMTGLSLIALGTGGIKPCVAAFGGDQFEEKHVQERNKFFSVFYLAINAGSLISTFLTPVLRGGVQCFGGDCYALAFGVPAALMIVALVVFISGNRLYKKIPPQGNILLEVCKCIVFALRNRIRNRSPEIPKREHWLDWASEKYSNQLITEVKMVTRVLFLFIPLPMFWALFEQQGSRWTLQATKMNANFERFVLQPDQMQFLNPLLILVFIPVFDFGLYPLVNLCRLNFTPIKKMATGMILASLAFAAAAIVELKLEENGMPIPVPKESYIQVLNLADSDVELTLEGYDLFRQPIKPFQDPAEYSRLILNSDQQFIQVKIQHQGLSSTYNHSIDEMSVNSLIIYKRGGNLTTNIIEDMQKKPSEGMAAVRFINTLEWDVGITLGEEEFITVNKSYGVSDYRTLPRGRYNNAKFQMKAEVSALKLGLLDFGASYTVVLTQASTEELQAWKIEDIPANNVHISWQIPQYLLMSAGEVMFSISGLAFSYSQAPVNMKSVLQAGWLLTVAFGNMIVLIVAQSAPLVQWAEFILFAMLLFIVFVIFSIMGYFYISTDPEELADKGNEHETSSNKNMIGLVTRKTKL",
"proteome": "UP000504612",
"gene": "SLC15A2",
"go_terms": [
{
"identifier": "GO:0022857",
"name": "transmembrane transporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0055085",
"name": "transmembrane transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0006857",
"name": "oligopeptide transport",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "03980fe80fd29f5043b13de7a766dbc1745073d3",
"counters": {
"domain_architectures": 12048,
"entries": 10,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 1,
"cathgene3d": 1,
"cdd": 1,
"panther": 1,
"pfam": 1,
"prosite": 2,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 12048
}
}
}