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{
    "metadata": {
        "accession": "A0A6J0UDX7",
        "id": "A0A6J0UDX7_9SAUR",
        "source_organism": {
            "taxId": "103695",
            "scientificName": "Pogona vitticeps",
            "fullName": "Pogona vitticeps (central bearded dragon)"
        },
        "name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase",
        "description": [
            "Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis"
        ],
        "length": 709,
        "sequence": "MSEASPTEFRGISRYKIETQGSKELRGCVTLRYIPSFVVNVSNMELDGVEQRNQKLSKAEKKLRQKQMKARHTLWKHEGIECVSYPTKSLVIANGGLGNGVSRCQLLCVVEKCGLVEVLSMPPNKPYSFVKYGMLEDATRAYNSLNGNKIKVEDSLQSVVLYFNFVEQVPWEDMTPPALPPGLSIIEELISPEEERQLLESIDWAEDEALPNTQKSLKHRRVKHFGYEFRYDNNNIDRDRPLPGGLPDICNTFLEKCLNMGYIKDSPDQLTINQYEPGQGIPPHIDTHSAFEDEIISLSLGAEIVMDFKHPDGRTLAVMLPQRSLLVMSGESRYLWTHGITPRKFDIVQASEGQQVGTITADTGNLTLNKRGTRTSFTFRKVRRSPCPCSYPSVCDSQRKDTAPAFPDNEREALELEKKYVHEVYEEIAMHFSNTRHSPWPRVVEFLRTLPCGAVVADVGCGNGKYLGVNKDLYLFGCDRSKTLVDICGEKGFQAFVGDALSVPIRSGSCDACISIAVIHHFATVERRLMTLSEIVRLLRPGGRALIYVWALEQEYNKQKSKYLKGKRAGSEKEGEIICNTATDTGDSGCRDLLHCSENVTQLEGRQYSANQIFPNELPVHTNRTSFDSQDLLVPWHLKDGTKKSTKQAKVHHPSANSSNVQDCPPVFHRYYHVFCEGELEQLCRRLGGITVQESYYDQGNWCVVLEKQ",
        "proteome": "UP001652642",
        "gene": "ALKBH8",
        "go_terms": [
            {
                "identifier": "GO:0003676",
                "name": "nucleic acid binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008757",
                "name": "S-adenosylmethionine-dependent methyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "9157eaf34b18aa0229af39d14a77d5f9a5d5ea98",
        "counters": {
            "domain_architectures": 450,
            "entries": 23,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 5,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "ssf": 3,
                "cdd": 2,
                "pfam": 3,
                "profile": 1,
                "panther": 1,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 450
        }
    }
}