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{
"metadata": {
"accession": "A0A6I8NZC3",
"id": "A0A6I8NZC3_ORNAN",
"source_organism": {
"taxId": "9258",
"scientificName": "Ornithorhynchus anatinus",
"fullName": "Ornithorhynchus anatinus (Duckbill platypus)"
},
"name": "Anaphase-promoting complex subunit 4",
"description": [
"Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins"
],
"length": 791,
"sequence": "MPAFRQVGEKQLPQEIIYMAWSPKRDLIALANRVGEVLLHRLANFQRVWSLPPNENTGKEVTSLAWRPDGKILAFGLADTKKVILCDVEKPESLHSFSVDTTITYMHWMEVTEESSVLTSFYNAEDESNLLLPKLPALPKNYSTTAKIFSEEKSDEIMKLLGDVRLNALVLGGDAGFIEIYAYGMYKIAMVTGVAGSCLGLCLSSDLKSLSVITEVQVSGDCSPEITYFQLDTSLLSSYLPEVTRMARKFTHISTLIQYIKLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMQLLLWGKASLELQALLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSEALLYHLSELKGMALWKQKYEPLGLDATGIEDAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYVAMLRMSEDHVLPELNKAPELYNRKGKYFNVERVGQYLKDEDDDLVSPPNTEGNQWFDFLQNSTHLKESPLLFPCFPQKSLHFVKRRMEEIIDHCLQKPADVIGKSVHQAICMPLYKSAKSEDSTPRLFKLPFLWNDKSSNLHYVLFTMLESSVSKIYILRRHTDISRPANHGLLALEFGNFMNTTSDNLEGSFYSCLDAHFYDDETITVVLKENSELEGKERVLAQLPLASIYPDEEHAEKEFSGTPGKRLDEQSDVIPTHTVLLESQWRVLENMKAQYVAVNGIRKVSCVLSSNLRHVRVFEMDVEDDGEVEEEEEEEEEEEEEEEEEEEFHNGPGEQEALNQSADKQDSSVCGGSAGLVEEAEEAESNLDT",
"proteome": "UP000002279",
"gene": "ANAPC4",
"go_terms": [
{
"identifier": "GO:0005515",
"name": "protein binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0030071",
"name": "regulation of mitotic metaphase/anaphase transition",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0031145",
"name": "anaphase-promoting complex-dependent catabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005680",
"name": "anaphase-promoting complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "a66af225d0df3ca015e8fdc5b080cf486be1aca7",
"counters": {
"domain_architectures": 1028,
"entries": 14,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"pfam": 3,
"pirsf": 1,
"panther": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 1028
}
}
}