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{
    "metadata": {
        "accession": "A0A6B0RCX1",
        "id": "A0A6B0RCX1_9CETA",
        "source_organism": {
            "taxId": "72004",
            "scientificName": "Bos mutus",
            "fullName": "Bos mutus (wild yak)"
        },
        "name": "Methylmalonic aciduria type A protein, mitochondrial",
        "description": [
            "GTPase, binds and hydrolyzes GTP. Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT). Plays a dual role as both a protectase and a reactivase for MMUT. Protects MMUT from progressive inactivation by oxidation by decreasing the rate of the formation of the oxidized inactive cofactor hydroxocobalamin (OH2Cbl). Additionally acts a reactivase by promoting the replacement of OH2Cbl by the active cofactor AdoCbl, restoring the activity of MMUT in the presence and hydrolysis of GTP"
        ],
        "length": 421,
        "sequence": "MNIPMLLQRPHQHFLKGLVRTPFRCYRFIFHPSPHLGSGVPCAQPLSSPGLHCAKWMLPSNGLTRKLCLQTTLEEHTEGLSDKEQRLVDKLYAGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLAHHREQENLNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGGGYDIILVETVGVGQSEFAVADMVDMFILLLPPAGGDELQGIKRGIVEMADLVAITKSDGDLIVPARRIQAEYVSALKLLRRRSGVWRPKVIRISARSGEGITEMWDKMKEFQEVMLVSGELAAKRQKQQKVWMWNLIQENVIEHFRTHPAVREQIPLLEKRVLSGALSPGLAADLLLKAFKSRHE",
        "proteome": "UP000322234",
        "gene": "E5288_WYG016375",
        "go_terms": [
            {
                "identifier": "GO:0003924",
                "name": "GTPase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005525",
                "name": "GTP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "55403b17a9be0643383e4d6e5af8f55858d8be16",
        "counters": {
            "domain_architectures": 15093,
            "entries": 11,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "ssf": 1,
                "cdd": 1,
                "pfam": 1,
                "panther": 1,
                "ncbifam": 2,
                "interpro": 2
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 15093
        }
    }
}