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{
    "metadata": {
        "accession": "A0A673T896",
        "id": "A0A673T896_SURSU",
        "source_organism": {
            "taxId": "37032",
            "scientificName": "Suricata suricatta",
            "fullName": "Suricata suricatta (Meerkat)"
        },
        "name": "Lysophosphatidylserine lipase ABHD12",
        "description": [
            "Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes. Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system. Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways. Has a strong preference for very-long-chain lipid substrates; substrate specificity is likely due to improved catalysis and not improved substrate binding"
        ],
        "length": 407,
        "sequence": "MRKRTEPVALEHERCAASGLSSGSAAAALDVDCRLKQNLRLAGKGPAEPRCTADAGMKRALGRRKSLWFRLRKILLCVLGLYVAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQGLNHTCNYYLQPEEDVTIGVWHTVPAVWWKDAQGKDQMWYEDALASSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALYVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCSLLILHAEDDPVVPFQLGRKLYNIAAPSRSFRDFKVQFIPFHSDLGYRHKYIYKSPELPRILRVEQRTVKRGQVALPTCCKLVSL",
        "proteome": "UP000472268",
        "gene": "ABHD12",
        "go_terms": null,
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "4208e7859dea7ff67287230d6f84ba11d78c698d",
        "counters": {
            "domain_architectures": 386493,
            "entries": 6,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "cathgene3d": 1,
                "pfam": 1,
                "panther": 1,
                "interpro": 2
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 386493
        }
    }
}