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{
    "metadata": {
        "accession": "A0A5E4C607",
        "id": "A0A5E4C607_MARMO",
        "source_organism": {
            "taxId": "9995",
            "scientificName": "Marmota monax",
            "fullName": "Marmota monax (Woodchuck)"
        },
        "name": "DnaJ homolog subfamily C member 2",
        "description": [
            "Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation"
        ],
        "length": 626,
        "sequence": "MLLLPSAADGQGTAITHALTSASALCQVEPVGRWFEAFVKRRTRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEIRQQALLAKKEKDIQKKAIKKERQKLRNSCKTWNHFSDNEAERVKMMEEVEKLCDRLELARSRKGCSGKTEEINEQIRKEKEEAEARMRQASKNAEKSTGGGGSSSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGIKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKVVFEFIDSIIICNVVSILVTAVKWELVEMVKAKKAAQEQVLNASRLKK",
        "proteome": "UP000335636",
        "gene": "GHT09_001718",
        "go_terms": [
            {
                "identifier": "GO:0030544",
                "name": "Hsp70 protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0043022",
                "name": "ribosome binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006450",
                "name": "regulation of translational fidelity",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0051083",
                "name": "'de novo' cotranslational protein folding",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "fb127eeab32ebccd576532cf809bf4e05bbf511d",
        "counters": {
            "domain_architectures": 918,
            "entries": 31,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cdd": 3,
                "ssf": 2,
                "cathgene3d": 3,
                "smart": 2,
                "pfam": 4,
                "profile": 4,
                "panther": 1,
                "prosite": 1,
                "interpro": 11
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 918
        }
    }
}