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{
    "metadata": {
        "accession": "A0A452VCI9",
        "id": "A0A452VCI9_URSMA",
        "source_organism": {
            "taxId": "29073",
            "scientificName": "Ursus maritimus",
            "fullName": "Ursus maritimus (Polar bear)"
        },
        "name": "Methylcytosine dioxygenase TET",
        "description": [
            "Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development"
        ],
        "length": 2004,
        "sequence": "MEQDRTNHVEGNRLSPFLTPSPSPICQTEPLALKLQNGSPLTERPYPEVNGDTKWQSFKSYYGIPPMKRSQNSRVSPDFIQEGRGYSRCLQNGGIKRTVSEPSLFGLHQNKKLRQDQKANGERKNFGESQERNPGKGSSQLNVSDLSDKRESVSSVARENAVKDFISFSTHNCSRSEKPGLQVLNEQEEKNANYRDKNIVLLLKNKAVLMPNGATVSASSMENTHGELLEKTLSQYYPDCVSVAVQKTTSHIHAINSQATNELSCEITHPSHTSGQINVPQTSNSELPPEPVAVVTEACDADKASKTAAVIGTCPFQKPEKQKSVFDICLSRAENSPIQGTTKLVSGEEFCSGSSSNLQAPSGSSERYLKQNETNGAYFKQSSVFTKDSFSAPTTPSPSQLLLSPPPPLPQVSQLPSEGKSTLNEGVLEEHHHYPNQSNTALLREVKIEGQPDAQPSLSPNPSTHASNHSLMLPERPQNNCVNKNDMQTLGSMTVPACSEKARQISEHLKHNPPILGSSGDPQDHCQQLMGHKEQDIPKGRDKEQTRGLVLPAQPYLKPGWIELKPPHFHQAESHPKCHEASLRSVLQYQSNPTNQTTSKQYTGNSSLPGGLPGQAYVQKIMQPEQRPQRYQGEMNQGQSQGTVDQQLQFQKPSLQVHFSKTDPSSKAHVQSVCTHRFYFEQRPDSQTEKLIPPTLKQHLNQQAPETEPFSSSHLLQHKPHKHTAQTQTQPSQNSLLSQNQQQQQKLQLKNKEQMPQAFSHPQDNSDQQREGSFFSQIKVEECFRGENQYFKSNEFQTHSTQMGSEQAQSVDSRNSPYGQILKSNASKLQISCSNNTHLVPKNKEQTINPELFAGNKTQNLHHRQYFPNNVTPKQDDLHRCFQEQEQKPPQASVLQGYRRRNQDMCSQQAAQVPQQRYLMQNQANAFPVSDRGAGHIQAPPQKDGQKHAALRWHLLQRQEQQQAQHPPTESCHDQMHRPIKVEPGSKPHTCMRPMSAQPENKTWKKMTKQEIPPPNCDNVQQRSILETMEQHLKQFQVKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTQALEQQATPSSEKTPTKRTAGSVLNNFLESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQIIEKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVVRRSCSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLYSELTETLRKYGTLTNRRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSKVPRKFKLLGDDPKEEEKLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAHAHRDLHNMQNGSTLVCTLTREDNREIGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEKKKQNGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSTNKNEKEKSASSRTKQTENASQAKQLAELLRLSGPVMQQSQQPPPPPLQKQAPQPQKPPPPPPPPQHHAMTHNPQSESVNSYSSPGSASLYMRRPNPVIQAYPSSSHTSDIYGGASPMNLYSTSSQATGSYLNSSNPMNPYTGLLNQNNQYPSYQCNGNVSVDNCSPYLGSYSPQPQPMDLYRYPNQDPLSKLNLPPIHTLYQPRFGNSQSFSSKYLGYGNQTMQGDAFSSCTLKTNVHHVGTFPPYSTHEMDGHFMGAASRLPPSLSSPNIDYKNGDHPPSSHIIHNYGAAPGVFNSSLHALHLQNKENDMLSHTANGFSKMLPGLSHDRTASGQEGLHKLQDAGNQEKQPSATEDNDEVWSDSEQSFLDPDIGGVAVAPTHGSILIECAKRELHATTPLKDPNRNHPTRISLVFYQHKSMNEPKHGLALWEAKMAEKAREKEEECEKYGPDYVPQKTHGKKVKREPTEPHEPSEPTYLRFIKSLAERTMSVTTDSTVTTSPYAFTRVTGPYNRYI",
        "proteome": null,
        "gene": "TET2",
        "go_terms": [
            {
                "identifier": "GO:0016706",
                "name": "2-oxoglutarate-dependent dioxygenase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0040029",
                "name": "epigenetic regulation of gene expression",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "a64ecb632ff246ce990334fabc8fc0f45b1aa404",
        "counters": {
            "domain_architectures": 3761,
            "entries": 7,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cdd": 1,
                "smart": 1,
                "pfam": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 3761
        }
    }
}