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{
    "metadata": {
        "accession": "A0A3Q2ZRL3",
        "id": "A0A3Q2ZRL3_KRYMA",
        "source_organism": {
            "taxId": "37003",
            "scientificName": "Kryptolebias marmoratus",
            "fullName": "Kryptolebias marmoratus (Mangrove killifish)"
        },
        "name": "RB1-inducible coiled-coil protein 1",
        "description": [
            "Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways. Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway through induction of RB1 expression. Plays a crucial role in muscular differentiation. Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis"
        ],
        "length": 1626,
        "sequence": "MKLYVFQVNNGSTLTFDTDLAVQTVLELKHAIQAKYKIAVQHQVLVVNGGECMAADRRVCSYSAGTETNPIFLFNKEMILSDRDPTIPKTTFSIESEIQVKVEESLLMPAVFHTVASRTQLALEMFEVAKKLCSFCERLVHDEHLQHQGWAAIMANLDDCALSYQKLLMKFNVAYTNYQQDLEEIKVKLSKLGTSVSVMARIPLLECLTRHSYRESIEKSSSTPGKDSDETEEEKSTDSVLCATQIPMPSKSSASLSASGTAACEPDGDQETNEMTDSGGLRAALLDEDVPELASQSVFNVTLLDWINVQDRPNDVESVVRKCFDSINRLDPRIIQPFLTECRDTIAKLDNQNMKSIKGLEDRLYALDQMIASCKKLVNEQKELAQGFLANQKRAENLKDTSVLPDLCLSHTNQLMIMLNNHRKLLDIKKKCTTAKQELANNLQVRLKWCCYVMLHADQDGEKLQALLRLLTELIERVRVVEALSTVPQMYCLAVVEVVRRKMFMRHYRAWANALVKDGKQLYEAEKFKRESFGKLFRKSFLRNRLFKGLDSWPPTSFCTRRPRRFDDELPDISLDDLQYLKSCCPAEVQPFLMVPTMCDFEPLNHHVESLHQLVQAAQSVDEMSQTITDLLSEQRVSCSLRAQRLTSLTRQSESKPGTTSSVSSKTPPSLSLQGPSCQPLHVPIPAPLEDLSPDSIDAQTFDFETIGHPNMDPVLQQGSLDLDSLAESPESDFMSAVNEFVIEENLTSPNPISDPTSPEMMVESLYSSVINAIDNKRMQDTTTLQKENSRIVELQKAVEKYKYAAEESHSNLRSVKDDLYYLRGLVVKEQHDFGLALVSMSSEVRTTVDEICQTHGTELKEQHQCELLSVRQELEKQVHALTEENQVNQSIVRDVQRAMLELEGLMERKEKELTQLENEKERWAVKESDLTDQIKDLEQINSDRTEEVNMLSASKDSLASQLENLHFEIERSQQKIRQELEAAAQCHLQELEDRMNQEHKTEMDSLNKNNQVALENLAVENNAKLTEATDHHATAIKEKELQIKDLEARLTELAELRCKLEVEVAFKESETEEVRILFEEAKSQQAEAINTQIEAETKVLRDELADFKRQLQAKNEEYEVDLAELRSLMRIEKDHCISELVNRHEEEAALLHTKVSTLQQQAQDAERNHAEQQQNLKEELLQQVAALSGEKEKQLRSFQELELELRTLLNNLQAENDLLSKKLEHDKHAIQKDGDKEAAPDVVAQEAFKELEQQKEKLEKELLDRIKQLEKELQEKQSLKSDDGLSLHADGRADAGAPLSLDSALQERLQQERASLQTQLELLERKKNEEMQNLKTSLIAEQQTNFNTVLTREKMKKEQVIRELTEKFQDVTQQQEKDKALIETLSEDRASLMQEKKHLEEELNRLRSSTTLVSSTFFSPNPSAPDASEPGAAAAAAARALPVAEACSSGLLYETDRLASVAAIQDDEQVDSAVEASMVAVHDNMMSEEKQRIILLERTLHMKEEENKRLSQRLMSQSMSSVSSRHSDKIAIRDFQVGDLVLIILDERHDNYVLFTVGPTLYFLHSESLTALDLKPASGTSRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVPWNRKV",
        "proteome": "UP000264800",
        "gene": null,
        "go_terms": [
            {
                "identifier": "GO:0000045",
                "name": "autophagosome assembly",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "1fe521c10d92d0d316906b6b0b3bab32b77ee4b9",
        "counters": {
            "domain_architectures": 3327,
            "entries": 8,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "cdd": 1,
                "pfam": 2,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 3327
        }
    }
}