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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A3Q0DI20",
"id": "A0A3Q0DI20_CARSF",
"source_organism": {
"taxId": "1868482",
"scientificName": "Carlito syrichta",
"fullName": "Carlito syrichta (Philippine tarsier)"
},
"name": "Amyloid-beta A4 protein",
"description": [
"Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis",
"The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis"
],
"length": 704,
"sequence": "MFCGKLNMHMNVQNGKWESDPTGTKTCITTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHPHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEDSDNIDSADAEEDDSDVWWGGADTDYADGSEDKVVEVTEEEEVADVEEEEADDDEDDEDGEEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLLKTTQESLPQDAVQLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVCVLCRRCGYKQRGDHWTHGGRCCHSNGDCHHLGDAEEETVHIHPSWCRGG",
"proteome": "UP000189704",
"gene": "APP",
"go_terms": [
{
"identifier": "GO:0008201",
"name": "heparin binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0046914",
"name": "transition metal ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004867",
"name": "serine-type endopeptidase inhibitor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "aad333249c83e7ee97cedb727ae5ad839f05ddb6",
"counters": {
"domain_architectures": 402,
"entries": 35,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 4,
"cathgene3d": 4,
"pfam": 4,
"smart": 2,
"profile": 3,
"cdd": 1,
"panther": 1,
"prints": 2,
"prosite": 2,
"interpro": 12
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 402
}
}
}