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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A340XWV1",
"id": "A0A340XWV1_LIPVE",
"source_organism": {
"taxId": "118797",
"scientificName": "Lipotes vexillifer",
"fullName": "Lipotes vexillifer (Yangtze river dolphin)"
},
"name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial",
"description": [
"NAD(P)H oxidoreductase involved in the ubiquinone biosynthetic pathway. Required for the O-methyltransferase activity of COQ3. Able to catalyze the oxidoreduction of 3-demethylubiquinone into 3-demethylubiquinol in vitro. However, it is unclear if 3-demethylubiquinone constitutes a substrate in vivo. May also play a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury"
],
"length": 396,
"sequence": "MGFLKTCVLRRNACTAVCFWRRQVVQKPSVRKISTTSPRSTVMPAWVIDKYGSNEVLRFTQNMMIPMIHYPNEVIIKVHAASVNPIDVNMRSGYGATALNMKRDPLHIKIKGEEFPLTLGRDVSGVVMECGLDVRYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHAQAASLPYVALTAWSAINKIGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGNMEEQLKYLKPFDFILDSVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKTLKHFWQGVHYRWAFFMASGPYLDDIAELVDAGKIQPVIEKTFPFSKVPEAFLKVERGHARGKTVVSVV",
"proteome": "UP000265300",
"gene": "RTN4IP1",
"go_terms": [
{
"identifier": "GO:0005739",
"name": "mitochondrion",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0016491",
"name": "oxidoreductase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008270",
"name": "zinc ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "37218a30e19a1dc4f38eb3bfb201e6a6601db95e",
"counters": {
"domain_architectures": 59802,
"entries": 17,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 2,
"cdd": 1,
"cathgene3d": 2,
"smart": 1,
"pfam": 2,
"panther": 1,
"prosite": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 59802
}
}
}