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{
"metadata": {
"accession": "A0A2Y9DDR4",
"id": "A0A2Y9DDR4_TRIMA",
"source_organism": {
"taxId": "127582",
"scientificName": "Trichechus manatus latirostris",
"fullName": "Trichechus manatus latirostris (Florida manatee)"
},
"name": "Polypyrimidine tract-binding protein 3",
"description": [
"RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U)"
],
"length": 524,
"sequence": "MNNSTSAPGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPNDVTEAEVISLGLPFGRVTNLLILKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAISAAQPGSLALSGAPTNEGTVLSGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYARMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFGPAIGFPQATGLSVSAVPGALGPLAIASSAVTGRMTIPGAGGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFTDAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALVELHNHDLGENHHLRVSFSKSTI",
"proteome": "UP000248480",
"gene": "PTBP3",
"go_terms": [
{
"identifier": "GO:0003676",
"name": "nucleic acid binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003723",
"name": "RNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006397",
"name": "mRNA processing",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005634",
"name": "nucleus",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "41e57ad083d6a04f9c691de8c8f2fc512151e2c2",
"counters": {
"domain_architectures": 5202,
"entries": 18,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"cdd": 2,
"profile": 1,
"smart": 1,
"pfam": 3,
"panther": 1,
"ncbifam": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 5202
}
}
}