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{
    "metadata": {
        "accession": "A0A2D0RXB5",
        "id": "A0A2D0RXB5_ICTPU",
        "source_organism": {
            "taxId": "7998",
            "scientificName": "Ictalurus punctatus",
            "fullName": "Ictalurus punctatus (Channel catfish)"
        },
        "name": "FERM, ARHGEF and pleckstrin domain-containing protein 2",
        "description": [
            "Functions as a guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion"
        ],
        "length": 1040,
        "sequence": "MGEIEGTYRALQTPGTRLGSQFNAGISTLEPGQSLNTSVAGGKGKSLQIRVQGLDDAQEFYELEAKADGQTLLNDVYRRINLIESDYFGLEFQNVQMNWVWLEPTKLIVKQVRRPMNTHFRLSVKFFPPDPGQLQEEFTKYLFSLQMKRDLIEGLLNCTENTAALLASHLVQSEIGDYDDVADREYLKLTKLLPHQEHFQEKIMELHRRHVGQTPAESDFQVLEIARKLEMYGVRFHPAADREGTKINLSVAHMGLLVFQGNTKINTFNWSKIRKLSFKRKRFLIKLHPEVHGPHQDTLEFLMASRDQCKIFWKSCVEHHAFFRLFDQPQPKAKAMLFSRGSSFRYSGRTQKQLVQYVRDSGVKRTPYQRRNSSKIRMSTRSLATDFPKQSLSFNDSLKICSSPPSATVSFHSLHSSISPVRMDNNSKPQIQQIQHISSLQQPVRPPTPVKEEPAKIHSPSNSAFPGPIMDSPQLSPFGSKCPLSVSTSFQMSTLSLPSQAPSSPVLNEGGSARLEEEEELRRKRYPTDKAYFIAKEILMTERTYLKDLEVITVWFRSAVIKENAMPEGLMTLLFSNIDPIYEFHRGFLKEIDQRLALWEGRSNAHVKGDYQRIGDVMLRNMCALKEFTSYLQKHDEVLTELEKATKRVKKLETVYKEFELQKVCYLPLNTFLLKPIQRLMHYKLILERLCKHYSPEHRDHHDCKEALKEVAEITAQLQTSLIRLENFQKLTELQRDLIGIENLTAPGREFIREGCLYKLTKKGLQQRMFFLFSDMLLYTSKGVTATNQFKVHGQLPLHGMLVEESENEWSVPHCFTIYSAQRTIVVAASSKVEMTKWIEDLNMAIDIAKKSQEKSEIFLDPSLCDRSNRSSDEVSLEQESEDDVNSSRCSLDKQSHHRANTTMHVCWHRNTSVSMSDHSLAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDFPLASLPLLGYTVSTPGESDSIHKEYVFKLQFKSHVYFFRAESEYTFERWMEVIKSAASAASRVTLLIPTGPEELNGN",
        "proteome": "UP000221080",
        "gene": "farp2",
        "go_terms": [
            {
                "identifier": "GO:0005085",
                "name": "guanyl-nucleotide exchange factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008092",
                "name": "cytoskeletal protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "56eb8623958804c4b813d5aec96d559ea2aa8435",
        "counters": {
            "domain_architectures": 2227,
            "entries": 49,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 8,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "smart": 5,
                "cathgene3d": 4,
                "cdd": 6,
                "profile": 3,
                "ssf": 4,
                "pfam": 6,
                "panther": 1,
                "prints": 2,
                "prosite": 1,
                "interpro": 17
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2227
        }
    }
}