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{
    "metadata": {
        "accession": "A0A1U7R804",
        "id": "A0A1U7R804_MESAU",
        "source_organism": {
            "taxId": "10036",
            "scientificName": "Mesocricetus auratus",
            "fullName": "Mesocricetus auratus (Golden hamster)"
        },
        "name": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]",
        "description": [
            "Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs. Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation"
        ],
        "length": 644,
        "sequence": "MAEDAEAAAESGGGGDPGVGAGERGVAPIKAQYRTTKERFHQYLEADKREDAGQESPAGDPDGSDPAEPEAKRIRLEDGQENGKTEVAAEPSEQPQMPRRARGQNKSRPHVKPTHYDKERLCPSLLQESATCAFGDRCRFLHDVGRYLETKPADLGPRCVLFDTFGRCPYSVTCRFAGAHLGPEGQNLVQDDVVARCVHLPPVRNGLSRALQQQLRKRQVCFERAEQALRRLTQGPKPVVPETTVATVTPEQNSCHAQLDTAGGASTPSGSPVPTCGPLTDEDIIRLRPCEKKRLDISGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHPCEDMFGVQLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGVNEVLDVPLTVKMRTGVQERVSLAHRLLPELRDWGVALVTLHGRSREQRYTRLADWPYIEQCAKLASPMPLFGNGDILSFEDANCAMQTGVAGVMIARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTHYGLEHWGSDTQGVERTRRFLLEWLSFLCRYVPVGLLERLPQRINERPPYYLGRDHLETLMASQQAADWIRISEMLLGPVPPGFAFLPKHKANAYK",
        "proteome": "UP000886700",
        "gene": "Dus3l",
        "go_terms": [
            {
                "identifier": "GO:0046872",
                "name": "metal ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0017150",
                "name": "tRNA dihydrouridine synthase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0050660",
                "name": "flavin adenine dinucleotide binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008033",
                "name": "tRNA processing",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "a849b7e5961d26bc7ca48c8f4324e7959298bf61",
        "counters": {
            "domain_architectures": 1018,
            "entries": 13,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "profile": 1,
                "pfam": 2,
                "cdd": 1,
                "ssf": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1018
        }
    }
}