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{
    "metadata": {
        "accession": "A0A1S4G128",
        "id": "A0A1S4G128_AEDAE",
        "source_organism": {
            "taxId": "7159",
            "scientificName": "Aedes aegypti",
            "fullName": "Aedes aegypti (Yellowfever mosquito)"
        },
        "name": "Probable ATP-dependent RNA helicase DDX46",
        "description": [
            "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, DDX46 plays essential roles during assembly of pre-spliceosome and proofreading of the branch site"
        ],
        "length": 1029,
        "sequence": "MTRPGENGKDRRRSRSHSPPDRKKRRSRSRERDRERTKTSFRFKDFGRRDRDRDRDREQRDREREKELEKERFKEAERKREREREREKLREQATKYAQSVSSSSGTSSTGFRQSKFDQKPPGYVEKEIKKPIKEEPKEKEETFDLSVPMDKEEEQRRLEQEMVKRRERIERWRAERKRKEIEIKKPTVLTGVNIPKKWSLEDDEEDDEDDIKDKANNNDEEDDVDPLDAFMKEVNEEVRKVNKLPSSAPKQDGKAASNSGVTIITGVAKKNTETTKKGELIEQNQDGLEYSSEEEQEDIKDTAANLANKQKKELAKIDHSGINYMPFRKAFYVEVPEIAKMTHAEVGVYKTELEGITVKGKGCPKPIKTWAHCGVSKKEFDVLRKLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPPLEDGDGPISIIMTPTRELCMQIGKDIKKFAKSLNLRAVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDLGFEPQVMRIIDNIRPDRQTVMFSATFPRQMEALARRILKKPIEIQIGGRSVVCKDVEQHVVVLEEDAKFFKLLELLGLYQELGSIIVFVDKQENADILLKDLMKASYPCLSLHGGIDQFDRDSTIIDFKQGRVKLLIATSVAARGLDVKQLILVVNYDCPNHYEDYVHRCGRTGRAGNKGFAWTFLTHEQGRYSGDIIRALELSGGTVPDDLRSLWDTYKAAQEAEGKKVHTGGGFSGKGFKFDEQEAAAVNERKKLQKAALGLQDSDDDDDLEQDIDQHIESMFATKRIVKEVEAPVITQSVSTPAPTTTNSDKLELAKRLASRINLQKNLGLEAKGATQQAAEAILKGGTTQQLITAKTVAEQLAAKLNTKLNYQPKDEDESPVESNETVFRKYEEELEINDFPQQARWKVTSKEALAQISEYSEAGLTVRGTYVPTGKTPPEGERKLYLAIESCSELAVTKAKREITRLIKEELLKLQASSHHIINKSRYKVL",
        "proteome": null,
        "gene": "AaeL_AAEL013985",
        "go_terms": [
            {
                "identifier": "GO:0003724",
                "name": "RNA helicase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003676",
                "name": "nucleic acid binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "2c10350622ba02ad2a316281bf64948ebbf48f1c",
        "counters": {
            "domain_architectures": 3841,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 5,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 3,
                "profile": 3,
                "smart": 2,
                "pfam": 3,
                "panther": 1,
                "prosite": 1,
                "interpro": 7
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 3841
        }
    }
}