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{
    "metadata": {
        "accession": "A0A1I8MHS6",
        "id": "A0A1I8MHS6_MUSDO",
        "source_organism": {
            "taxId": "7370",
            "scientificName": "Musca domestica",
            "fullName": "Musca domestica (House fly)"
        },
        "name": "Eukaryotic translation initiation factor 3 subunit F",
        "description": [
            "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation",
            "Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling"
        ],
        "length": 280,
        "sequence": "MSGLNLTVKVHPVVLFQVVDAYERRNADSHRVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEAELSYALDLYDLNRKVNPNENVVGWWATGNEVTNHSSVIHEYYARECNNPVHLTVDTSLQGGRMGLCAYVCIPLGVPGGKTGCMFTPIPVEMTCYEPETVGIKLLQKTIGNSAPHRTKTVSPMLDLAQISEAATKLQSLLELILKYVEDVIAHKQPPDNAVGRQLLDLIHSVPHMSHEQFTQMFNANVRDLLMVITLSNLIKTQLQLNEKLTYLPTN",
        "proteome": "UP001652621",
        "gene": "101901685",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008233",
                "name": "peptidase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008237",
                "name": "metallopeptidase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003743",
                "name": "translation initiation factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0031369",
                "name": "translation initiation factor binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006413",
                "name": "translational initiation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005852",
                "name": "eukaryotic translation initiation factor 3 complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "79d61d9b501010c6454254d3ae24b98b0961a92d",
        "counters": {
            "domain_architectures": 12662,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "pfam": 2,
                "smart": 1,
                "profile": 1,
                "cdd": 1,
                "panther": 1,
                "hamap": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 12662
        }
    }
}