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{
    "metadata": {
        "accession": "A0A1I7YSL5",
        "id": "A0A1I7YSL5_9BILA",
        "source_organism": {
            "taxId": "37863",
            "scientificName": "Steinernema glaseri",
            "fullName": "Steinernema glaseri"
        },
        "name": "Flavin-containing monooxygenase",
        "description": [
            "Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects",
            "Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine"
        ],
        "length": 537,
        "sequence": "MEGTRRVAIIGAAASGLPSTRHAVLYGFEPVVFEASDDIGGLWRFKKQDTDESSVMKSTIINTSKELTAYSDFPPPADFANFMHNEKVLEYLRLYAQHWDLLKYIRFRHKVFNIERSPSYEKTGSSKRFRTDEDTAEEFDGVVIALGHHCTPNFPPKWPGQDVFQGRIIHSHSYKDHKGLDDKVCVVVGVGNSGCDAAVELSRFAKMVYLVTRRGTWVYSRIFEHGVPYDIFLNSRFNAFMMSILPESTVCNYLENKLESRFDHANYGLKPAHRILGAHPTANDELPSRIASGMVCVKPNIKEFTETDVIFEDGTVAENVDLVVLATGYTYNFDIVENGKLIKVDRNKSDLYQFVFPLVTADHNTLAVVGYVQPLGSIMAVGEMQARLYFDALSGHTKLPSKEKMAKSVEMKRKEMARVYVDSQRHTIQVPYTPYMDEMANMIGCKPNLLAQFFTDPKLWWTLFFGPNVAYQYRLRGPHPWKDARQALLTLSERVVVPTRTREPPMTKPQGFPLVKTVTLLGICAAVGFHVYRSHLK",
        "proteome": "UP000095287",
        "gene": null,
        "go_terms": [
            {
                "identifier": "GO:0004499",
                "name": "N,N-dimethylaniline monooxygenase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0050660",
                "name": "flavin adenine dinucleotide binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0050661",
                "name": "NADP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "cea59a56e6d7a75ef5681f4b224bfc6672b76e85",
        "counters": {
            "domain_architectures": 47203,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "cathgene3d": 1,
                "panther": 1,
                "pfam": 1,
                "pirsf": 1,
                "prints": 2,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 47203
        }
    }
}