General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "A0A151MJC8",
        "id": "A0A151MJC8_ALLMI",
        "source_organism": {
            "taxId": "8496",
            "scientificName": "Alligator mississippiensis",
            "fullName": "Alligator mississippiensis (American alligator)"
        },
        "name": "Pleckstrin homology domain-containing family M member 2",
        "description": [
            "Plays a role in lysosomes movement and localization at the cell periphery acting as an effector of ARL8B. Required for ARL8B to exert its effects on lysosome location, recruits kinesin-1 to lysosomes and hence direct their movement toward microtubule plus ends. Binding to ARL8B provides a link from lysosomal membranes to plus-end-directed motility. Critical factor involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation"
        ],
        "length": 1052,
        "sequence": "MEPGEVKDRILHNISLSVKKLQSYFAACEDETPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLSLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFDLDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEGTSNYSGHVGGVWDFRWSLSRGQVAPLNQTLGFANTNESNITIPRGDYDFGDVFPAVPSMPSKVWEDGDLTDTLSCPRSVASDTNGSKVSVKSPTQRYNPFNEEKAEVVSSSETTPVHAASQERVDAATEGTDQSESCTELEVIRLAKKKKTGKKKKVKSEEVVNPSPSASAESSGDSGVNGLSDAAELQKASNPPCPEAVKGQERPEESGEHSALSQLGLRIPEMKDTSMESVGQPLSKVIDKLHGQLDPSGWTASVEPPDQSFRTGTPGETPDGPSSGDFSEGISTPMDFYRFTVESPNAPAPGGGNHDLAGDGQPSHVPGSPEAAGQEEKGGEGEAAGAVEDSQEGVAKPQAREAETASAEAPSKPKRDQPSPSLSSAEDSGVEEGQGSPSDTAHPSEFRVDNNHLLLLMIHVFRENEEQLFRMIRMSTGHMEGNLQLVYVLLTDCYIYLIRKGAAEKPYLVEEAVSYNELDYVSVGLDQQTVTLVCTNRRKQFLLDTADVALTEFFLVSLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASEVAVRFYGLVHWEDPMDEALGPAPSNYTSAENSVTKEGILHYKAGTSYLGKEQWKTCFVVLSNGILYQYPDRTEVTPLLSVTMGGEQCGGCRRSNTTERPHSFQVILTDRPSLELSAENEEEMADWMQYFCQAVSKGVIPQGVVPAPCIPCCLVIADEKVFTCHEDCQTSFFRSLGTVELTDVAAISTEAGKEYCIIEFAKDREQFLPPWVLYFSCTTELERFLSALSTIWKSIYQIDLLHKAIQEASVKKKCEDALSLIHSAWQRSDSLCRGRASRDPWC",
        "proteome": "UP000050525",
        "gene": "PLEKHM2",
        "go_terms": null,
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "873f9563e04900776cfe54cb7bb10c71e61f1bfe",
        "counters": {
            "domain_architectures": 1191,
            "entries": 21,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "cdd": 2,
                "profile": 2,
                "smart": 2,
                "pfam": 3,
                "panther": 1,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1191
        }
    }
}