General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "A0A125RK34",
        "id": "A0A125RK34_GIBSA",
        "source_organism": {
            "taxId": "42676",
            "scientificName": "Gibberella sacchari",
            "fullName": "Gibberella sacchari"
        },
        "name": "3-hydroxy-3-methylglutaryl coenzyme A reductase",
        "description": [
            "HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA). In this module, the cytosolic acetyl-CoA acetyltransferase catalyzes the formation of acetoacetyl-CoA. The hydroxymethylglutaryl-CoA synthase then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase HMGR"
        ],
        "length": 1182,
        "sequence": "MAAILLPNRFRGEAPVTEKTTPSWFSKRLTPVAQFLSRLACSHPIHTVVVVAVLASTSYVGLLQESLFNTGVESATLGKADWSSLVEGSRVLRAGPETAWNWKAVEQDAVADAGSDADHLALLTLVFPDSLSAESSSTAPRSHHVPIPQNLSITSLPSTENPFTAYSQDSILAYALPYSEGPEFLAAAQEIPNEDAVEIETKHGREKKTWIMKAAKVNTRNSVVQWVSNAWTEFLDLLKNAETLDIVIMLLGYIAMHLTFVSLFLSMRKMGSKFWLGICTLFSSVFAFLFGLVVTTKLGVPISVILLSEGLPFLVVTIGFEKNIVLTRAVMSHAIEHRRIQAQNSKSGKRSPERSMQNMIQYAVQAAIKEKGFEIMRDYAIEIVILVIGAASGVQGGLQQFCFLAAWTLFFDFILLFTFYTAILSIKLEINRIKRHVDMRMALEDDGVSRRVAENVAGDDELNRVRGDAPLFGRKSSSIPKFKVLMILGFIFVNIVNICSIPFRNPSSLSTIRTWASSLGGVIAPLSVDPFKVASNGLDAILATAKSNNRPTLVTVLTPIKYELEYPSIHYALGSAASNPAYDDAFHHHFQGYGVGGRMVGGILKSLEDPVLSKWIVIALALSVALNGYLFNVARWGIKDPNVPEHNIDRNELARAQQFNDTGAATLPLGEYVPPTPMRTQPSTPAITDDEAEGLHMTKARPANLPNRSNEELEKLLSEKRVREMTDEEIISLSMRGKIPGYALEKTLGDFTRAVKIRRSIIARNKATTDVTHSLDRSKLPYENYNWERVFGACCENVIGYMPLPVGVAGPLVIDGQSYFIPMATTEGVLVASASRGCKAINSGGGAITVLTADGMTRGPCVAFETLERAGAAKLWLDSEAGQDMMKKAFNSTSRFARLQSMKTALAGTNLYIRFKTTTGDAMGMNMISKGVEHALSVMANEGGFDDMQIISVSGNYCTDKKAAALNWIDGRGKGVVAEAIIPGEVVRSVLKSDVDSLVELNVAKNLIGSAMAGSVGGFNAHAANIVAAIFLATGQDPAQVVESANCITIMKNLNGALQISVSMPSLEVGTLGGGTILEPQGAMLDILGVRGSHPTNPGDNARRLARIIGAAVLAGELSLCSALAAGHLVRAHMQHNRSAAPSRSTTPAPPMTPVSLAMTSAQERSASTTSMSAAAIQRSKR",
        "proteome": null,
        "gene": "HGR1",
        "go_terms": [
            {
                "identifier": "GO:0016616",
                "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0015936",
                "name": "coenzyme A metabolic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004420",
                "name": "hydroxymethylglutaryl-CoA reductase (NADPH) activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008299",
                "name": "isoprenoid biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "c8361cda78ace185d3c1d61a11085c230c4d4768",
        "counters": {
            "domain_architectures": 1327,
            "entries": 27,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 2,
                "ssf": 2,
                "cathgene3d": 3,
                "cdd": 1,
                "pfam": 3,
                "panther": 1,
                "ncbifam": 1,
                "prosite": 3,
                "prints": 1,
                "interpro": 10
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 1327
        }
    }
}