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{
    "metadata": {
        "accession": "A0A0A0UE95",
        "id": "A0A0A0UE95_CAPHI",
        "source_organism": {
            "taxId": "9925",
            "scientificName": "Capra hircus",
            "fullName": "Capra hircus (Goat)"
        },
        "name": "NACHT, LRR and PYD domains-containing protein 3",
        "description": [
            "Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF"
        ],
        "length": 1031,
        "sequence": "MIMASVRCKLARYLEDLEDIDFKKFKMHLEDYPSQKGCTSIPRGQTEKADHVDIATLMIDFNGEEKAWAMAKWIFAAINRRDLYEKAKRDEPEWENTNVSVLSQEESLEEEWMGLLGYLSRISICRKKKDYCKKYRKYVRSKFQCIEDRNARLGESVNLNKRFTRLRLIKEHRSQQEREHELLAIGRTWAKIQDSPVSSVNLELLFDPEDQHSEPVHTVVFQGAAGIGKTILARKIMLDWASEKLYQDRFDYLFYIHCREVSLGTQRSLGDLIASCCPGPNPPIGKIVSKSSRILFLMDGFDELQGAFDEHTEALCTNWQKVERGDILLSSLIRKRLLPEASLLITTRPVALEKLQHLLGQARHVEILGFSEARRKEYFLKYFSDEQQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMDSGKSLARTSKTTTAVYIFFLSSLLQSQGGSQENHNSATLWGLCSLAADGIWNQKILFEECDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEDNHGEMRNMPQACSKLPNRDVKVLLENYGKFEKGYLIFVVRFLFGLINQERTSYLEKKLSCKISQKIRLELLKWIEAKAKAKTLQTEPSQLELFYCLYEMQEEDFVQRAMGHFPKIEIKLSTRMDHVVSSFCIENCRHVESLSLRLLHNSPKEEEEEEEVRHSHMDHSVLSDSEVAYSQGLVNYLTSSICRGIFSVLSNNWNLTELNLSGNTLGDPGMKVLCETLQQPGCNIRRLWLGQCCLSHQCCFSISSVLSSNQKLVELDLSHNALGDFGIRLLCVGLRHLFCNLKKLWLVSCCLTSASCEDLASVLSTNHSLTRLYLGENALGDSGVGILCEKVKNPHCNLQKLGLVNSGLTSGCCPALSSVLSTNQNLTHLYLQGNALGDMGVKLLCEGLLHHNCKLQVLELDNCSLTSHCCWDLSTLLTSNQSLRKLSLGNNDLGDLGVMLLCEVLKQQGCLLKSLRLCEMYFNYDTKRALETLQEEKPELTIVFEPSR",
        "proteome": "UP000291000",
        "gene": "NLRP3",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "fea8f1f75a5f0a0d7d90c5e8022f13c11d45e3b6",
        "counters": {
            "domain_architectures": 351,
            "entries": 30,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 2,
                "ssf": 3,
                "cathgene3d": 3,
                "smart": 3,
                "pfam": 6,
                "cdd": 2,
                "panther": 1,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 351
        }
    }
}