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{
"metadata": {
"accession": "A0A096N590",
"id": "A0A096N590_PAPAN",
"source_organism": {
"taxId": "9555",
"scientificName": "Papio anubis",
"fullName": "Papio anubis (Olive baboon)"
},
"name": "F-box only protein 43",
"description": [
"Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Plays a vital role in modulating the ubiquitilation of CCNB1 and CDK1 during gametogenesis"
],
"length": 707,
"sequence": "MNFKDKDERISCLEYVTLSSKSSRFTDQTEILKMSQKHSGQAGTEAGNGVDSPPIVNSKYSTFRDFCSTSSFQDSGYNELKSCSFDNTDKEYLGKEVKGPTLLHEHPETSGLGLTHSLESPTQKKKFILPGKENDKTPELCETPKISGKKCLPRRRLHVSFSLLKGDFESQNSALESSISQVLNLEKNIPSSASGFSRANNFSPLVTSTLKTEEVTSCSQKLRLNFSQQKTSTIDDSKDDCSLFEVECISPIQGNDFKDSITHDFSDSSLCINDENACPELLGSSVSGTTCGTDEDIFVTPISNLVANIRFNASQILSPSPEVRGNISTPEDSGFNSLSLEKSEDSLSDQEGSFQELLQKHKGTPKVGDTIRKTRHLGRSRRLSTLREQSSQSETEEEKQIVHPDSEKRAAAASAISEGQLSGDESGDLTFSLKNLSKTPALQLVHELFMKSKRKRFQENSGHEFLEQGNGEKIAVLQCILAGLIGKKMGIEKLDILTELKYRNLKHILAMVLDSLTAESLCSVWKVSRNWREIVVQDKNANRRRKFYITQLKTDSEGAVLNVEDAATRLQLLNRSALRSVQAQARIPGSQREQGSTLSPWGEVLTPLASSSVTHLSSKQEEYVKVAKTLFIDEALKPCPRCQSPAKYQPYKKRGLCSRTACGFDFCVLCLCAYHGSEECSRGAAKPRNRKDALPGSAQSKRNLKRL",
"proteome": "UP000028761",
"gene": "FBXO43",
"go_terms": [
{
"identifier": "GO:0005515",
"name": "protein binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008270",
"name": "zinc ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0007088",
"name": "regulation of mitotic nuclear division",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0045835",
"name": "negative regulation of meiotic nuclear division",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "a8ccb41538c99065411e5e00ddf58598a4ca4b97",
"counters": {
"domain_architectures": 105,
"entries": 14,
"isoforms": 0,
"proteomes": 1,
"sets": 4,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 2,
"cathgene3d": 2,
"cdd": 2,
"smart": 1,
"ssf": 1,
"profile": 1,
"panther": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 105
}
}
}