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{
    "metadata": {
        "accession": "A0A076EBV7",
        "id": "A0A076EBV7_OCHPR",
        "source_organism": {
            "taxId": "9978",
            "scientificName": "Ochotona princeps",
            "fullName": "Ochotona princeps (Southern American pika)"
        },
        "name": "Interleukin-6",
        "description": [
            "Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells"
        ],
        "length": 216,
        "sequence": "MNSVFASALRPAPVGFALGLLLVVATAFPTAPSVSMKEEPQGGATSDKPFTPVKIESTISYILMKISDIRKKMCNYDANCLDCKQVLSDVNLTLPQLTERDGCFPSAPNQEICLMRITAGLLEFEIYLKHLQNKFKSDEENNNMDIVLQNSQTLVKTLRPKVKTTEEAPTLEPATLTSLKENMQLKEQWRRTQTIHYILCGLKDFLEFTLRAVRLM",
        "proteome": null,
        "gene": "IL6",
        "go_terms": [
            {
                "identifier": "GO:0005138",
                "name": "interleukin-6 receptor binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0030154",
                "name": "cell differentiation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005615",
                "name": "extracellular space",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0005125",
                "name": "cytokine activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006955",
                "name": "immune response",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005576",
                "name": "extracellular region",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "ca3c816964203ca148b2a41a888b8b5a391e3f49",
        "counters": {
            "domain_architectures": 1063,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "pfam": 1,
                "ssf": 1,
                "smart": 1,
                "panther": 1,
                "prints": 2,
                "prosite": 1,
                "interpro": 4
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 1063
        }
    }
}