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{
    "metadata": {
        "accession": "PF25094",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR056961",
        "hierarchy": null,
        "name": {
            "name": "PUS7L R3H domain",
            "short": "R3H_PUS7L"
        },
        "description": [
            {
                "text": "<p>This R3H domain is found in human Pseudouridylate synthase PUS7L and related proteins. PUS7L catalyzes pseudouridylation of mRNAs [[cite:PUB00155816]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00155816": {
                "PMID": 35051350,
                "ISBN": null,
                "volume": "82",
                "issue": "3",
                "year": 2022,
                "title": "Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing.",
                "URL": null,
                "raw_pages": "645-659.e9",
                "medline_journal": "Mol Cell",
                "ISO_journal": "Mol Cell",
                "authors": [
                    "Martinez NM",
                    "Su A",
                    "Burns MC",
                    "Nussbacher JK",
                    "Schaening C",
                    "Sathe S",
                    "Yeo GW",
                    "Gilbert WV."
                ],
                "DOI_URL": "https://doi.org/10.1016/j.molcel.2021.12.023"
            }
        },
        "set_info": {
            "accession": "CL0879",
            "name": "R3H-like"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 6,
            "interactions": 0,
            "matches": 961,
            "pathways": 0,
            "proteins": 961,
            "proteomes": 686,
            "sets": 1,
            "structural_models": {
                "alphafold": 889,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 2176
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 28,
            "alignment:full": 740
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}