General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "PF23024",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR025110",
        "hierarchy": null,
        "name": {
            "name": "Disco-interacting protein 2-like, AMP domain",
            "short": "AMP-dom_DIP2-like"
        },
        "description": [
            {
                "text": "<p>This domain is found in Disco-interacting protein 2 from Drosophila melanogaster (DIP2) and similar sequences from eukaryotes and bacteria. DIP2 is required for precise axonal bifurcation in mushroom body neurons and may play a role in fatty acid metabolism. This protein harbours one DNA methyltransferase 1-associated protein 1-binding (DMAP1- binding) domain ([pfam:PF06464]) and two AMP-dependent synthase (AMP) domains (this entry) [[cite:PUB00097529]]. This domain is often found associated to [pfam:PF00501] and shows an alpha-beta configuration.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00097529": {
                "PMID": 27908785,
                "ISBN": null,
                "volume": "421",
                "issue": "2",
                "year": 2017,
                "title": "DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons.",
                "URL": null,
                "raw_pages": "233-244",
                "medline_journal": "Dev Biol",
                "ISO_journal": "Dev Biol",
                "authors": [
                    "Nitta Y",
                    "Yamazaki D",
                    "Sugie A",
                    "Hiroi M",
                    "Tabata T."
                ],
                "DOI_URL": null
            }
        },
        "set_info": {
            "accession": "CL0531",
            "name": "AMP-binding_C"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 532,
            "interactions": 0,
            "matches": 15358,
            "pathways": 0,
            "proteins": 15353,
            "proteomes": 4546,
            "sets": 1,
            "structural_models": {
                "alphafold": 4339,
                "bfvd": 0
            },
            "structures": 9,
            "taxa": 10828
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 76,
            "alignment:full": 8416
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}