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{
    "metadata": {
        "accession": "PF21667",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR048895",
        "hierarchy": null,
        "name": {
            "name": "Nop5, N-terminal domain",
            "short": "Nop5_N"
        },
        "description": [
            {
                "text": "<p>This entry represents the N-terminal domain of archaeal Nop5, a Nop56/58 homologue which are pre-RNA processing ribonucleoproteins (RNP). This domain is very well conserved and mediates a stable interaction with fibrillarin, playing a role in both RNP assembly and methyltransferase activity [[cite:PUB00059437]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00059437": {
                "PMID": 22496443,
                "ISBN": null,
                "volume": "287",
                "issue": "23",
                "year": 2012,
                "title": "Structurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase Activity.",
                "URL": null,
                "raw_pages": "19418-28",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Gagnon KT",
                    "Biswas S",
                    "Zhang X",
                    "Brown BA 2nd",
                    "Wollenzien P",
                    "Mattos C",
                    "Maxwell ES."
                ],
                "DOI_URL": null
            }
        },
        "set_info": {
            "accession": "CL0759",
            "name": "Nop_N_sf"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 2,
            "interactions": 0,
            "matches": 40,
            "pathways": 0,
            "proteins": 38,
            "proteomes": 16,
            "sets": 1,
            "structural_models": {
                "alphafold": 37,
                "bfvd": 0
            },
            "structures": 1,
            "taxa": 50
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 3,
            "alignment:full": 6
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "3t7z",
            "name": "Structure of Methanocaldococcus jannaschii Nop N-terminal domain"
        }
    }
}