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{
    "metadata": {
        "accession": "PF18281",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR040747",
        "hierarchy": null,
        "name": {
            "name": "BILBO1 N-terminal domain",
            "short": "BILBO1_N"
        },
        "description": [
            {
                "text": "<p>This is the N-terminal domain of BIBLO1 present in Trypanosoma brucei. BILBO1 is a flagella pocket collar component. Depletion of BIBLO1 prevents flagella pocket and flagella pocket collar biogenesis and leads to cell death. This domain has a ubiquitin-like fold and has a conserved patch of four aromatic residues (Phe-12, Trp-71, Tyr-87, and Phe-89) and three basic residues (Lys-15, Lys-60, and Lys-62) [[cite:PUB00091242]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00091242": {
                "PMID": 24362019,
                "ISBN": null,
                "volume": "289",
                "issue": "6",
                "year": 2014,
                "title": "Structure of the TbBILBO1 protein N-terminal domain from Trypanosoma brucei reveals an essential requirement for a conserved surface patch.",
                "URL": null,
                "raw_pages": "3724-35",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Vidilaseris K",
                    "Morriswood B",
                    "Kontaxis G",
                    "Dong G."
                ],
                "DOI_URL": "https://doi.org/10.1074/jbc.M113.529032"
            }
        },
        "set_info": {
            "accession": "CL0072",
            "name": "Ubiquitin"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 3,
            "interactions": 0,
            "matches": 97,
            "pathways": 0,
            "proteins": 97,
            "proteomes": 29,
            "sets": 1,
            "structural_models": {
                "alphafold": 91,
                "bfvd": 0
            },
            "structures": 3,
            "taxa": 81
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 2,
            "alignment:full": 30
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "7a1i",
            "name": "Crystal structure of the BILBO2/FPC4 complex"
        }
    }
}