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{
    "metadata": {
        "accession": "PF08595",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR013904",
        "hierarchy": null,
        "name": {
            "name": "RXT2-like, N-terminal",
            "short": "RXT2_N"
        },
        "description": [
            {
                "text": "<p>The family represents the N-terminal region of RXT2-like proteins.  In S. cerevisiae, RXT2 has been demonstrated to be involved in conjugation with cellular fusion (mating) and invasive growth [[cite:PUB00033323]].  A high throughput localisation study has localised RXT2 to the nucleus [[cite:PUB00016470]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00033323": {
                "PMID": 10628851,
                "ISBN": null,
                "volume": "262",
                "issue": "4-5",
                "year": 1999,
                "title": "Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach.",
                "URL": null,
                "raw_pages": "683-702",
                "medline_journal": "Mol Gen Genet",
                "ISO_journal": "Mol. Gen. Genet.",
                "authors": [
                    "Entian KD",
                    "Schuster T",
                    "Hegemann JH",
                    "Becher D",
                    "Feldmann H",
                    "Guldener U",
                    "Gotz R",
                    "Hansen M",
                    "Hollenberg CP",
                    "Jansen G",
                    "Kramer W",
                    "Klein S",
                    "Kotter P",
                    "Kricke J",
                    "Launhardt H",
                    "Mannhaupt G",
                    "Maierl A",
                    "Meyer P",
                    "Mewes W",
                    "Munder T",
                    "Niedenthal RK",
                    "Ramezani Rad M",
                    "Rohmer A",
                    "Romer A",
                    "Hinnen A."
                ],
                "DOI_URL": "http://dx.doi.org/10.1007/PL00013817"
            },
            "PUB00016470": {
                "PMID": 14562095,
                "ISBN": null,
                "volume": "425",
                "issue": "6959",
                "year": 2003,
                "title": "Global analysis of protein localization in budding yeast.",
                "URL": null,
                "raw_pages": "686-91",
                "medline_journal": "Nature",
                "ISO_journal": "Nature",
                "authors": [
                    "Huh WK",
                    "Falvo JV",
                    "Gerke LC",
                    "Carroll AS",
                    "Howson RW",
                    "Weissman JS",
                    "O'Shea EK."
                ],
                "DOI_URL": "http://dx.doi.org/10.1038/nature02026"
            }
        },
        "set_info": null,
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        "counters": {
            "subfamilies": 0,
            "domain_architectures": 20,
            "interactions": 0,
            "matches": 1356,
            "pathways": 0,
            "proteins": 1338,
            "proteomes": 1086,
            "sets": 0,
            "structural_models": {
                "alphafold": 1171,
                "bfvd": 0
            },
            "structures": 3,
            "taxa": 2337
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 58,
            "alignment:full": 916
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}