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{
    "metadata": {
        "accession": "PF05704",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR008441",
        "hierarchy": null,
        "name": {
            "name": "Capsular polysaccharide synthesis protein",
            "short": "Caps_synth"
        },
        "description": [
            {
                "text": "<p>This family consists of several capsular polysaccharide proteins. Capsular polysaccharide (CPS) is a major virulence factor in Streptococcus pneumoniae [[cite:PUB00011291]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00016014": {
                "PMID": 7752885,
                "ISBN": null,
                "volume": "15",
                "issue": "1",
                "year": 1995,
                "title": "Region II of the Haemophilus influenzae type be capsulation locus is involved in serotype-specific polysaccharide synthesis.",
                "URL": null,
                "raw_pages": "107-18",
                "medline_journal": "Mol Microbiol",
                "ISO_journal": "Mol. Microbiol.",
                "authors": [
                    "Van Eldere J",
                    "Brophy L",
                    "Loynds B",
                    "Celis P",
                    "Hancock I",
                    "Carman S",
                    "Kroll JS",
                    "Moxon ER."
                ],
                "DOI_URL": "http://dx.doi.org/10.1111/j.1365-2958.1995.tb02225.x"
            },
            "PUB00011291": {
                "PMID": 11179285,
                "ISBN": null,
                "volume": "69",
                "issue": "3",
                "year": 2001,
                "title": "Molecular characterization of Streptococcus pneumoniae type 4, 6B, 8, and 18C capsular polysaccharide gene clusters.",
                "URL": null,
                "raw_pages": "1244-55",
                "medline_journal": "Infect Immun",
                "ISO_journal": "Infect. Immun.",
                "authors": [
                    "Jiang SM",
                    "Wang L",
                    "Reeves PR."
                ],
                "DOI_URL": "http://dx.doi.org/10.1128/IAI.69.3.1244-1255.2001"
            },
            "PUB00019248": {
                "PMID": 9838125,
                "ISBN": null,
                "volume": "1443",
                "issue": "1-2",
                "year": 1998,
                "title": "Molecular structure of the gene cluster responsible for the synthesis of the polysaccharide capsule of Streptococcus pneumoniae type 33F.",
                "URL": null,
                "raw_pages": "217-24",
                "medline_journal": "Biochim Biophys Acta",
                "ISO_journal": "Biochim. Biophys. Acta",
                "authors": [
                    "Llull D",
                    "Lopez R",
                    "Garcia E",
                    "Munoz R."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/S0167-4781(98)00213-9"
            },
            "PUB00015956": {
                "PMID": 10094675,
                "ISBN": null,
                "volume": "181",
                "issue": "7",
                "year": 1999,
                "title": "acs1 of Haemophilus influenzae type a capsulation locus region II encodes a bifunctional ribulose 5-phosphate reductase- CDP-ribitol pyrophosphorylase.",
                "URL": null,
                "raw_pages": "2001-7",
                "medline_journal": "J Bacteriol",
                "ISO_journal": "J. Bacteriol.",
                "authors": [
                    "Follens A",
                    "Veiga-da-Cunha M",
                    "Merckx R",
                    "van Schaftingen E",
                    "van Eldere J."
                ],
                "DOI_URL": "http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=10094675&action=stream&blobtype=pdf"
            },
            "PUB00019249": {
                "PMID": 10688204,
                "ISBN": null,
                "volume": "403",
                "issue": "6770",
                "year": 2000,
                "title": "The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.",
                "URL": null,
                "raw_pages": "665-8",
                "medline_journal": "Nature",
                "ISO_journal": "Nature",
                "authors": [
                    "Parkhill J",
                    "Wren BW",
                    "Mungall K",
                    "Ketley JM",
                    "Churcher C",
                    "Basham D",
                    "Chillingworth T",
                    "Davies RM",
                    "Feltwell T",
                    "Holroyd S",
                    "Jagels K",
                    "Karlyshev AV",
                    "Moule S",
                    "Pallen MJ",
                    "Penn CW",
                    "Quail MA",
                    "Rajandream MA",
                    "Rutherford KM",
                    "van Vliet AH",
                    "Whitehead S",
                    "Barrell BG."
                ],
                "DOI_URL": "http://dx.doi.org/10.1038/35001088"
            }
        },
        "set_info": {
            "accession": "CL0110",
            "name": "GT-A"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 80,
            "interactions": 0,
            "matches": 2979,
            "pathways": 0,
            "proteins": 2965,
            "proteomes": 1285,
            "sets": 1,
            "structural_models": {
                "alphafold": 2427,
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            },
            "structures": 0,
            "taxa": 3207
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 28,
            "alignment:full": 1365
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}